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Stem cells in nasal polyposis
Chronic rhinosinusitis with nasal polyps (CRSwNP) is common and is multifactorial with increased T-helper 2 response and active role of interleukin 5. It can be associated with asthma and control of CRSwNP improves lower airway disease. Due to constant cellular...
The hot nose
Capsaicin nasal spray can offer moderate to significant symptomatic relief to 70-80% of patients with idiopathic rhinitis (IR). Efficacy was also shown in lab studies. Nasal hyper reactivity (NHR), absence of allergy / infective rhinosinusitis, age limits (18-60), no anatomical...
Nasal nitric oxide – an inflammatory marker in paediatric allergic rhinitis?
Nasal nitric oxide (nNO) is mainly produced in the paranasal sinus mucosa and was shown in some studies to have increased expression in allergic rhinitis (AR). Although it represents a potential non-invasive tool for AR measurement, there remains no consensus...
Blocked nose in children with allergic rhinitis
Nasal obstruction is a classic symptom in children with allergic rhinitis. While the nasal obstructive disorders including septal deformity, turbinate hyperplasia and adenoidal enlargement are widely recognised in adult nasal blockage, their relationship with paediatric allergic rhinitis however, is scarcely...
Growing up smelling the roses
How often do we ask about sense of smell in children? Undoubtedly, the olfactory function is seldom formally assessed in the paediatric population, although evidence exists to suggest its potential links with handicap in children’s learning and development. This large...
Is the lack of sunshine the reason behind allergic rhinitis?
Deficiency in Vitamin D, an in vogue immunomodulator, has been shown in emerging data to have a substantial pathogenetic role in allergic related diseases, particularly asthma. The concept of a shared upper and lower airway has allowed the natural extrapolation...Across the pond: a tale of two fellowships
Where in the world is Halifax? Many outside of Canada have never heard of the Maritime Canadian town of Halifax. Before leaving to start a year-long fellowship there, we both had to answer many questions from family and friends about...
