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Clinicopathological features of follicular variant of papillary thyroid carcinoma

The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...

Head and neck cancer and PET-CT

Positron emission tomography-computed tomography (PET-CT) is an imaging technique in which abnormalities of tissue metabolism are precisely superimposed onto the anatomy. It relies on the premise that malignant cells are more metabolically active compared with non-malignant cells. On this basis,...

How will our grandchildren view COVID-19?

Alan Johnson, known to our readers as the former President of ENT UK, gives us his thoughts on the COVID pandemic, looking at it through the lens of other health crises. As I write, COVID-19 is displacing almost all other...

Measuring audiological outcomes in the paediatric setting

In this article Marlene Bagatto argues that a range of outcome measures and instruments need to be implemented when working with children and families. She demonstartes how these support both clinicians and families. The primary goal of early hearing detection...

Standards for Safe Listening – how they align and how some differ

The ‘Make Listening Safe workgroup’ is an initiative of The World Health Organization (WHO) in the framework of the World Hearing Forum and is committed to creating a world where nobody’s hearing is put in danger due to unsafe listening....

Tinnitus in patients on therapy with PPI and in PPI non–users

Tinnitus is a chronic and debilitating condition and approximately 10% of the population is afflicted. A myriad of pharmacological treatments for tinnitus are available but only a few controlled studies have shown positive results. The relationship between proton pump inhibitors...

Olfactory and gustatory recovery in coronavirus patients after six months

It remains unclear for how long olfactory and gustatory losses persevere in patients with COVID-19. This is a prospective study of 300 patients who lost taste and smell within seven days of contracting COVID-19. The patients were objectively assessed with...

The role of cVEMPs in the diagnosis of Meniere’s disease

This study sets out to determine the most useful metrics to use from cervical-vestibular evoked myogenic potential (c-VEMP) tests when the diagnosis of Meniere’s disease (MD) is unclear, or as a follow-up tool. It is known that cVEMPs can detect...

Zinc and rhinosinusitis

Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...

Sinonasal undifferentiated carcinoma – slowly getting there

The rarest of the rare, sinonasal tumours form only a small part of the total number of head and neck tumours and undifferentiated carcinoma (SNUC) is one of the rarest of this group. There is some data (and some expert...

Lymph node ratio is a significant predictor for loco-regional recurrence after neck dissection in patients with papillary thyroid cancer

Lymph node metastases are common in papillary thyroid cancer (PTC), yet the impact of nodal metastases on survival remains unclear. Lymph node density (LND) is the ratio between the number of positive lymph nodes excised and the total number of...

To monitor the nerves or not?

Whilst intraoperative nerve monitoring has become the standard of care for mastoid and parotid surgery, its benefit in thyroid surgery remains unclear. In the UK NICE was agnostic on the subject in 2008, stating that it was potentially helpful and...