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Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

Meeting myself coming back

Sometimes, it can seem like trainers and trainees are separate entities, inhabiting separate worlds, in two separate spheres of experience. However, trainees become trainers, and there is always a period where the trainer has only just stopped being the trainee....

Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

Mastoid surgery for cholesteatoma

Landmark Paper: Toner JG, Smyth GDL. Surgical Treatment of Cholesteatoma: a comparison of three techniques. Am J Otol 1990;11(4):247-9. Canal wall up or canal wall down? Chris Aldren discusses the landmark paper that attempted to provide a definitive answer for...

Laryngology (Otorhinolaryngology - Head and Neck Series)

A fantastic overview of the various aspects of laryngology including clinical assessment and diagnoses, disorders of the larynx and basic anatomy and physiology. Each chapter is divided into short sub-sections making it easy to follow and access specific topics. Each...

The role of prediction and gain in tinnitus

Dr Will Sedley is a Clinical Academic Neurologist who has done groundbreaking work in the field of tinnitus mechanisms. Here, he introduces and explains the concepts of prediction and of gain as they relate to troublesome tinnitus. This article focuses...

Elasticated retraction in head and neck surgery – a trainee’s perspective

The effectiveness of surgical technique and satisfactory outcome is greatly dependent on good surgical exposure. Retraction requires adequate traction and counter-traction of tissues in order to expose the tissue or organ under scrutiny for the surgeon. This is a universal...

Doing it for the men: diversifying the speech and language therapy profession

It is known that many health professions are dominated by females, particularly the allied health professions, such as speech and language therapy. This is more pronounced in the US than in the UK, Australia and other countries. The authors of...

Does the season affect the diagnosis of vestibular disorders?

There are mixed results in the literature regarding seasonal variation in the presentation of various peripheral vestibular disorders. In this large population study involving over 20,000 patients recruited from 116 ENT practices across Germany, the authors analysed the demographic characteristics...

Work and the risk and carcinoma of the larynx

This is a census on the national cancer registry in France to detect professions at a higher risk of squamous cell carcinoma of the larynx. During the period 2001-2016 there were 244 registered cases of cancer of the larynx. Amongst...

Lingual tonsils and obstrucive sleep apnoea syndrome (OSAS)

Obstructive sleep apnoea can be due to narrowing of the retrolingual space by hypertrophic lingual tonsils. The authors studied 11 patients (five males and six females with a mean age of 44.3 years and a mean BMI of 28.6). All...

An unrecognised anatomical variant which may help frontal sinus surgery

Anatomic variants in the frontal sinus have significant implications in endoscopic sinus surgery. In this illustrative study, the authors describe a newly-observed anatomical variant – a mucosa lined prism‑shaped space between the most superior part of the nasal septum and...