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Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Tramadol soaked nasal packs for post-septoplasty analgesia

Having had a septoplasty a number of years ago for the potential treatment of snoring, I was intrigued by this paper which compared the analgesic effect of tramadol-soaked and lignocaine-soaked nasal packs following septoplasty. In my practice, I have always...

Speech perception in the ageing population

Speech perception can present a challenge as we grow older. One of the factors responsible is, of course, hearing loss. Now research indicates that other non-auditory factors like cognitive decline may also contribute to difficulties in understanding speech. The authors...

Maturation of BC attenuation

The aim of this study was to clarify the reason for differences between bone-conduction hearing in adults and infants. The authors investigated how the sound pressure level in the ear canal changes depending on the bone-conduction transducer placement. By using...

Close monitoring of patients for delayed hyponatremia post-transsphenoidal surgery

he incidence of delayed hyponatremia is 16-28% and usually accounts for unplanned readmission of the patient within 30 days after transsphenoidal surgery. One of the surrogate measures of quality of care adopted by the government and regulatory agencies is 30-day...

Same, same: similarities in conversation between people with dementia and aphasia and their loved ones

This article proposes that studying the commonalities between the effect of dementia and aphasia (post stroke language impairment) on communication could result in greater sharing of clinically relevant interventions. To date the separate study has resulted in significant separation of...

Balloon dilatation is an effective adjunct

This is a good study design, sufficiently powered, comparing medical management to balloon sinus dilatation. All patients had failed medical management and were thoroughly assessed preoperatively with Lund-Mackay score confirming abnormal CT findings, SNOT 20 index score, chronic sinusitis score...

Which technique is better for cholesteatoma surgery?

There continues to be debate over the benefits and limitations of different techniques for cholesteatoma surgery. This retrospective review of 132 cases over a 10 year period with primary cholesteatoma from Turkey tried to establish which technique [canal wall up...

Surgery for hypopharyngeal obstruction causing OSA

Surgical treatments for OSA are evolving with improved diagnostic accuracy of the level(s) involved. Where the collapsing segment lies below the soft palate, a variety of surgical techniques to correct the affected segment(s) are emerging. This article concentrates on one...