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1582 results found

Noise induced hearing loss caused by nightclubs

Legislation on hearing loss and tinnitus, occurring due to noise exposure at work, has been well established in terms of protection and compensation, but the same damage resulting from noise in nightclubs remains an open issue. This study, based on...

The stubborn polyp cases are ‘different’

The widely different behaviour of nasal polyp disease between patients is a major feature of rhinology practice and makes counselling of patients difficult when approaching their first operative intervention. Setting aside aspirin sensitivity (Samter’s triad), which is known to be...

Eosinophilic or not eosinophilic: dupilumab seems to work

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...

Medication and its effect on the larynx

This article summarises different medications and their effect on the voice. A growing number of patients we see in clinic are on multiple medications that could affect vocal cord function. The author summarises different classes of medications and their potential...

Systemic steroid therapy for reduction of macrophage migration inhibition factor in the control of nasal polyposis

It is believed that macrophage migration inhibitory factor mediates inflammation by stimulating the release of other pro-inflammatory cytokines. The use of systemic steroids in control of nasal polyposis is an established treatment. In this study the authors have aimed at...

Nasal disease and quality of life in athletes

Rhinitis is a nasal condition which is generally underappreciated in primary care and even less in athletes. In this study, the authors specify nasal symptoms constituting rhinitis as nasal blockage, sneezing bouts, rhinorrhoea and itching and compare their prevalence in...

A new criterion for diagnosing chronic tonsillitis?

It is essential to establish the diagnosis of recurrent tonsillitis in patients undergoing tonsillectomy. This is based mainly on history which itself can be inaccurate and is supported by clinical findings which are not truly specific. There seems to be...

Steroids for vocal cord mucus retention cysts

This is an interesting paper that describes the use of intralesional steroid injections to treat vocal cord mucus retention cysts. The gold standard is microlaryngoscopy and excision of the lesion. In patients who may be unable to undergo surgery, this...

Globus – benign when the sole symptom

This is a prospective cohort study of Danish patients that presented to an otolaryngologist’s office with globus over the course of a year. They accounted for 4% of new patients, amounting to 122 patients in this study (57 patients were...

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Are cardiovascular risk factors associated with hearing loss?

Cardiovascular disease (CVD) risk factors are associated with microvascular damage that can impair molecular transport across capillary walls and cause inflammation and oxidative stress that may damage cochlear structure and function. This study determined, among a population-based sample of Canadian...

A new biomarker for chronic rhinosinusitis

This Chinese study looked at the feasibility of periostin (usually found in bone and lung tissue) as a biomarker for chronic rhinosinusitis. They sampled ethmoid mucosa in 12 patients with chronic rhinosinusitis without nasal polyposis (CRSsNP) and 25 patients with...