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103 results found

The role of the multidisciplinary team in laryngology and airway – the Charing Cross experience

As the National Centre for Airway Reconstruction, the Charing Cross laryngology MDT provides expert care to patients with airway problems as well as voice and swallowing disorders. In this article, the team explain their raison d’etre and why the MDT...

The integration of targeted therapy and surgery in advanced thyroid cancer clinical trials

One of the headline speakers, Mark Zafereo, will be talking at IFOS about thyroid cancer. We hear from his team about some of the areas they will be discussing. Locally advanced thyroid cancer generally refers to patients who have significant...

Recent advances in the diagnosis of silent reflux

The vexed topic of reflux always generates much discussion, particularly when it comes to testing. We hear about a non-invasive assay that is gaining in popularity. Voice disorders impact around four percent of the UK population and can significantly hamper...

What’s new in laryngology: the next 10 years!

At a time of unprecedented technological advances, Taran Tatla and Jonathan Fishman gaze into the laryngological crystal ball… Introduction The recent explosion in science, technology and innovation takes us into a new era, with the opportunity and capability to transform...

Oesophageal atresia and trachea-oesophageal fistula: a perspective on dysphagia management from Turkey

Children born with oesophageal atresia with or without trachea-oesophageal fistula usually receive early surgical repair to create tension-free anastomosis that facilitates oral feeding. However, many children are at risk of problems related to subsequent dysphagia. This includes respiratory, nutritional, motility...

Can diet alone be used to treat laryngopharyngeal reflux?

In this crossover observational study, a low-fat, low-quick-release sugar, high-protein, alkaline, and plant-based diet was investigated as a single treatment for laryngopharyngeal reflux (LPR). Authors recruited 50 participants with demonstrated LPR on hypopharyngeal-oesophageal multichannel intraluminal impedance-pH-monitoring (HEMII-pH), off acid suppressive...

GORD and CRS – is there an association?

This international collaboration assessed 32 papers which had published original data on the experimental, diagnostic, treatment or prognostic association between GORD and CRS. The study aims to systematically review the evidence for a role of GORD in CRS. Case control,...

What is the relationship between swallowing difficulties and underlying mental health issues?

People living with dysphagia often experience mental health difficulties. This study aimed to identify whether pre-existing anxiety and depression impacted patient scores on a patient-reported swallowing outcome measure, the Eating Assessment Tool (EAT-10) where a score of ≥3 is indicative...

Predicting swallowing outcomes post radiotherapy for head and neck cancer

A videofluroscopic swallow study (VFSS), also known as modified barium swallow (MBS) offers a dynamic view of swallow biomechanics and associated swallowing physiology. The authors of this paper investigated whether quantitative timing and displacement measures of key structures involved in...

Salivary pepsin – a simple test for LPR?

A diagnosis of laryngopharyngeal reflux (LPR) can be made on the basis of characteristic symptoms and nasendoscopy findings. Objective tests exist for this condition; for example, 24-hour dual-channel pH-metry which is considered to be the gold standard. Such tests are,...

Association of childhood OME with obesity

Many factors influence the development of otitis media with effusion (OME) in children, some of them being increased plasminogen factor inhibitor (PAI-1) levels, eustachian tube obstruction and gastro-oesophageal reflux. These factors are also associated with obesity. Sixty children with mean...

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...