You searched for "nose"

1318 results found

A modification of the crescentic flap for nasal skin reconstruction

Non-melanoma skin cancers are the most frequent skin tumours and in over 25% of cases affect the nose. Following excision, the reconstruction may be challenging. Reconstruction aims to preserve the anatomical units, nasal functions and also an aesthetic final outcome....

OTO-104 in noise-induced and cisplatin-induced hearing loss

These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...

Lymph node ratio is a significant predictor for loco-regional recurrence after neck dissection in patients with papillary thyroid cancer

Lymph node metastases are common in papillary thyroid cancer (PTC), yet the impact of nodal metastases on survival remains unclear. Lymph node density (LND) is the ratio between the number of positive lymph nodes excised and the total number of...

Consider PCR testing in culture negative necrotising otitis externa

Necrotising otitis externa (NOE) often does not yield identification of a causative organism to treat although in 90% of cases it is a member of the pseudomonas species. The incidence of fungal NOE is not to be forgotten and this...

Management of necrotising otitis externa

Although uncommon, necrotising (previously malignant) otitis externa (nOE) can be very aggressive, particularly if not managed appropriately. In this study the authors perform a retrospective review of 25 patients admitted with nOE over a four year period at a tertiary...

How has management and outcomes of necrotising otitis externa changed over the past decade?

Necrotising otitis externa (NOE) remains a challenging condition for ENT departments, particularly with the increased prevalence of diabetes mellitus (DM) in the general population. There is no international consensus on treatment, although many institutions now have local guidelines drawn up...

New MRI technique assesses treatment response in skull base osteomyelitis

This paper describes another useful imaging technique to monitor Necrotising Otitis Externa (NOE). Echoplanar diffusion weighted magnetic resonance (DW MR) shows high signal on the ‘ADC map’ with active disease and this reduces in signal intensity as symptoms improve. This...

A new approach to workplace hearing conservation

The traditional approach to managing workplace noise has failed - how can we better protect our nation’s hearing using smart hearing protection? Occupational noise-induced hearing loss (ONIHL) is the most common occupational health condition in the world and the most...

Role of sentinel lymph node biopsy in managing papillary thyroid cancer

Although studies have shown that the presence of lymph nodes metastases in papillary thyroid carcinoma does not alter survival, other studies have shown that it increases morbidity and mortality and that the presence of cervical lymph node metastasis at diagnosis...

Noise induced hearing loss caused by nightclubs

Legislation on hearing loss and tinnitus, occurring due to noise exposure at work, has been well established in terms of protection and compensation, but the same damage resulting from noise in nightclubs remains an open issue. This study, based on...

Do personal listening devices cause cochlear synaptopathy?

Cochlear synaptopathy is a condition in which noise interrupts the synaptic communication between sensory inner hair cells and low spontaneous rate cochlear nerve fibres. Since these nerve fibres are associated with signal coding in noisy backgrounds, their disruption leads to...

Hidden hearing loss in humans: cochlear synaptopathy is superseded by cognitive effects when listening to speech in noise

Elizabeth Beach presents an overview of the recent research being undertaken at the National Acoustic Laboratories on speech in noise and its relationship to cochlear synaptopathy. Our team at the National Acoustic Laboratories (NAL) has been investigating hidden hearing loss...