You searched for "multichannel"

105 results found

Those little friends in our noses

Human microbiota plays an important role in both health and disease including metabolism, immunomodulation, and a potential role in chronic inflammatory conditions such as chronic rhinosinusitis (CRS). The authors aimed to investigate the sinonasal microbiome using 16S rRNA gene sequencing...

Does use of pectoralis muscle myocutaneous flap (PMMCF) reduce postoperative pharyngocutaneous fistula complication after salvage laryngectomy?

Salvage laryngectomy for recurrent laryngeal carcinoma following failed radiotherapy or chemoradiotherapy is associated with high postoperative complication rate. The primary aim of this paper was to assess whether use of muscle myocutaneous flap (PMMCF) as an interposition graft reduces the...

Merocel vs Cutanplast Anal packing

This study compared two different nasal dressings after septoplasty. Seventy-six patients acted as their own controls by having one nostril packed with Merocel and one nostril somewhat improbably with Cutanplast Anal (gelatin sponge). It seems that the gelatin sponge was...

Nasal septoplasty: is it more effective than medical management?

Question1. How do we know that undertaking an operation will benefit a patient? Question 2. How do policy makers / health systems know an operation is effective and ‘good value for money’? As trained professionals, we spend our careers seeking...

Eosinophilic or not eosinophilic: dupilumab seems to work

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...

Clinical histopathology of 250 parotidectomy patients

Clinical histopathology of 250 parotidectomy patients This is a retrospective study of 250 consecutive parotidectomy patients at units in Belgium and the Netherlands. The sensitivity and specificity of FNAC was 64% and 99% respectively, the sensitivity being slightly lower than...

Salvage surgery vs. repeat stereotactic radiosurgery for progressing vestibular schwannomas

This large multicentre case series of patients treated twice with stereotactic radiosurgery (SRS) for progressing vestibular schwannomas (VS) is reported by the International Gamma Knife Radiosurgery consortium. Progression of tumour growth after primary SRS is rare but does occur. Complications...

A global survey of tracheostomy healthcare provision and patient participation: requirements for improvement

Patients with tracheostomy require comprehensive care which should begin in the preoperative phase and go through immediate postoperative and discharge phases with patient involvement as well. The authors assessed this with a multicentre, cross-sectional survey using a mailing list held...

Applying ‘Sal classification’ to parotid cytology to replicate the success of the Thy classification system

The usefulness of the Thy classification in thyroid gland disease has led to attempts to generate a similar cytology classification for parotid lesions. However, the accuracy of fine-needle aspiration cytology in salivary gland disease is more variable because of the...

Sublingual house dust mite immunotherapy

House dust mite immunotherapy in allergic rhinitis was shown to be effective in trials with a relatively small number of participants. The authors of this study performed a multicentre double-blind randomised controlled trial to investigate effects of house dust mite...

A new hydrogel dural sealant for CSF repair

This paper reports the findings of a multicentre prospective randomised trial conducted to demonstrate the efficacy of the Adherus Dural Sealant for FDA approval. The Adherus Dural Sealant was compared with the control, DuraSeal Dural Sealant. It was applied to...

Vestibular schwannoma surgery and inner ear injuries

Iatrogenic inner ear injury during vestibular schwannoma (VS) surgery ranges between 20% and 30% in the literature. However, there is no up-to-date quantification of such injuries, hence this study. The authors conducted a US-multicentre database search looking for patients who...