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Present and future in myringoplasty

Tympanic membrane perforations are a common finding in ENT practice. Whilst watchful waiting or formal tympanoplasty are standard options – wouldn’t it be amazing if there was a low cost, safe, in-clinic option to immediately help patients (I hear you...

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

DP Medical brings pioneering sinus surgery wound healing gel to the UK

DP Medical Systems Ltd. has been named as the exclusive UK and Ireland supplier of Chitogel™ – a pioneering wound healing gel for use in endoscopic sinus surgery.

What’s happened since the European position paper on nose and sinus tumours?

The management of malignant sinonasal tumours has gone through radical changes in recent years. Prof Valerie Lund gives us an update based on her upcoming talk at IFOS. In 2010 when we published the European position paper on ‘endoscopic management...

Wound moisture sensing in traumatic wounds

Wounds can be small and unpleasant, or may be large and life-threatening. The skin is a physical and an immunological barrier to infection, and any defect in the integrity of the skin may enable bacterial or fungal invasion. The successful...

eNOS and OME

The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...

The use of THRIVE in laryngology and phonosurgery

The team in Lewisham has been using THRIVE for our phonosurgical cases for about a year. Here, we discuss the pros, cons and potential pitfalls of setting up and using THRIVE as ventilation during anaesthesia rather than using an ML...

Discovery in the genetics of complex disease: Otitis media

Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...

NSC- HHT – a systematic review of intranasal Bevacizumab

This systematic review of 13 studies concerning the use of an anti-angiogenic nasal treatment in the management of epistaxis in HHT patients finds no significant effect. This paper looked at four RCTs, three prospective studies, three retrospective, one case series...

DVT prophylaxis in cranial procedures

Deep vein thrombosis (DVT) is a result of disturbed balances in blood flow patterns, blood clotting factors promoting coagulation and vessel wall endothelial injury. The subsequent disruption of coagulation and fibrinolysis mechanisms lead to venous clot formation and propagation. The...

Clinical value of 3 T magnetic resonance imaging after intratympanic gadolinium injection in cases of delayed endolymphatic hydrops

Recurrent vertigo can continue after severe unilateral or bilateral hearing loss. This is a condition similar to Ménière’s disease, the diagnosis of which can be difficult. In this study intratympanic injection of gadolinium-diethylenetriamine penta-acetic acid dimeglumine was done in 25...

Laryngotracheal stenosis and malacia care

Why laryngotracheal stenosis and malacia (LTSM) care matters now? In late 2019, reports began to emerge of severe respiratory infections caused by a novel coronavirus. In the months that followed, intensive care admissions in the UK rose more than tenfold....