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Pre-clinical development of magnetic delivery of therapy to middle and inner ears

1 March 2014 | | ENT, Otology
Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...

Temporal bone trauma

1 July 2014 | | ENT, Head and Neck, Skull Base Surgery
Introduction Temporal bone injuries represent one of the more complex management problems presenting to the otolaryngologist. This is largely due to difficulties in assessment and the frequent delays in referral, often as a result of other injuries demanding more immediate...

Genetic discovery using animal models: presbyacusis

1 November 2014 | | ENT, Genetics, Otology
By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

The changing spectrum of cancer of the oropharynx: dilemmas and future directions

1 March 2016 | | ENT, Laryngology / Swallowing / Voice, Head and Neck
The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....

Aetiology, investigation and acute management of sudden sensorineural hearing loss

1 September 2015 | | Audiology - Adult, Audiology - Diagnostic
The cause of a single sided sensorineural hearing loss has a wide variety of aetiologies. This review, by Edwin Halliday, looks specifically at the differential diagnostic causes of a sudden sensorineural hearing loss, the relevant investigations and the management should...

Will it ever happen?

1 November 2014 |
Audiology is a rapidly evolving field, with many exciting developments on the horizon. David Baguley identified some topics of interest, and asked some international experts ‘will it ever happen?’ Gene therapy for deafness After years of development, gene therapy for...

Endoscopic Dacryocystorhinostomy

1 September 2014 | | Rhinology / Sinus
Epiphora, or abnormal tearing, occurs because of blockage in the lacrimal drainage system, which impairs normal tear channeling into the nose. Dacryocystorhinostomy (DCR) is used to treat patients diagnosed with lacrimal sac or nasolacrimal duct obstruction (NLDO). External DCR was...

New ventilation technique FCV: improvement for patient, anaesthetist/intensivist and surgeon

1 September 2020 | | ENT, Laryngology / Swallowing / Voice
Per-oral surgical access to the larynx can be hampered by the presence of an endotracheal tube. Various systems have been developed for tubeless ventilation, but these all carry a risk of aerosolisation of secretions with obvious inherent risks. We hear...

Functional Endoscopic Sinus Surgery (FESS) - Part 2

1 November 2016 | | Rhinology / Sinus
In the first of this two-part series, Martyn Barnes and colleagues discussed indications for functional endoscopic sinus surgery (FESS), the surgical objectives and techniques, patient expectations and the risks of surgery [1]. In this second and final part, the authors...

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

1 November 2014 | | ENT, Genetics
Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

Practical training courses for otolaryngology trainees

1 March 2017 | | ENT
In this extended Trainee Matters, it’s a pleasure to present a trio of excellent articles with a theme of practical training courses for otolaryngology trainees. Miss Rachel Edmiston, Professor Nirmal Kumar and colleagues have written a valuable guide to setting...

2014: Are today’s implantable devices better than conventional solutions for patients with conductive or mixed hearing loss?

6 June 2017 | | Audiology - Adult, Audiology - Paediatric, Auditory Implants, ENT, Otology, Paediatric ENT
Patients with conductive or mixed hearing loss become candidates for amplification when reconstructive surgery is not viable. Three common amplification options are conventional acoustic devices, such as behind-the-ear devices (BTEs), (implantable) bone-conduction devices and active middle ear implants. The goal...