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The structure and function of DNA
DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...
Antioxidants for bacterial rhinosinusitis
This Turkish laboratory animal-based study looked at the effects of alpha-lipoic acid on inflammation, oxidative status, and tissue integrity in an animal model of experimentally induced acute rhinosinusitis and to compare these effects with antibiotic treatment using cephalosporins. Alpha-lipoic acid...Salivary duct clipping for drooling
Drooling can be a challenging problem to manage in paediatric ENT. The variety of medical and surgical treatments suggests that there is no gold standard treatment. Nicola Stobbs and Ravi Thevasagayam describe an approach to ligating the salivary ducts. Drooling...Functional Endoscopic Sinus Surgery (FESS) - Part 2
In the first of this two-part series, Martyn Barnes and colleagues discussed indications for functional endoscopic sinus surgery (FESS), the surgical objectives and techniques, patient expectations and the risks of surgery [1]. In this second and final part, the authors...The development of endoscopic sinus surgery – a meeting of three great minds
The story of the development of endoscopic sinus surgery is inextricably linked with the names of Stammberger, Messerklinger and Storz. Karl Storz’s daughter, Sybill Storz, tells us more. We would like to take this opportunity to express our appreciation of...
Sarcoidosis and the nose
This retrospective case note review from Mount Sinai in New York looked at just 14 patients with sarcoidosis. Individual ENT units in the UK are likely to see relatively few of these patients, unless there is a major tertiary referral...
Inner ear immunity
There is much speculation regarding the ear’s immune response. The environment in which we live and breathe is getting ever more complex; aspects such as the percentage of the population with autoimmune conditions are on the rise and, therefore, it...
What is in the Fountain of Youth?
Does the auditory system have to age? Can we become more like turtles or jellyfish and keep our internals running without degradation? This essay considers the theoretical underpinnings of biological processes in the cochlear, in particular the role of the...
