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Long-term results for dupilumab are very promising!
Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...
Vestibular schwannoma surgery and inner ear injuries
Iatrogenic inner ear injury during vestibular schwannoma (VS) surgery ranges between 20% and 30% in the literature. However, there is no up-to-date quantification of such injuries, hence this study. The authors conducted a US-multicentre database search looking for patients who...
Paediatric hearing following chemotherapy
This study examined the effect of platinum compounds on hearing in 104 children with solid tumours. As would be expected, this group was heterogeneous and included a range of ages, tumour types, chemotherapeutic agents and dosing regimens. Age-appropriate audiometry was...
MRI and the endolymphatic space
This is an interesting study which was performed to evaluate the endolymphatic space in patients with endolymphatic hydrops (EH), using MR imaging. Seven patients aged between 21–77 years; five female, two male with unilateral or bilateral symptoms of EH were...
Which bone conduction implant (BCI) device to use?
Bone conduction implants (BCI) are alternatives when the use and benefit of conventional, prosthetic equipment is limited or contraindicated in patients who suffer from conductive, mixed and single-sided deafness. They are broadly divided into two main groups delivering vibration directly...
Learning curve for sialendoscopy
Sialendoscopy represents a minimally invasive technique that permits direct salivary tree visualisation and treatment using endoscopic techniques. Previous studies have shown that it is an efficacious, safe and potentially gland preserving method to treat major salivary gland disease. However, it...
Day care stapes surgery
This paper reports on a proposed unblinded, randomised controlled trial in which the hearing outcomes after inpatient stapes surgery will be compared with those after day case stapes surgery. The study is currently in the recruitment stage and plans to...
Impaired music perception in children with specific language impairment
This study compares musical skills of children with typical language development with those of children with specific language impairment. Both groups received a test consisting of a melody and a song identification along with a test battery to assess receptive...
MRI evaluation to assess the role of frusemide in reducing endolymphatic hydrops
Endolymphatic hydrops is generally considered to be a marker in Ménière’s disease and frusemide is used with the purpose of reducing it and improving symptoms. With the use of MRI, the authors have used the phenomenon of non-enhancing endolymphatic structures...
Do spreader grafts improve nasal airflow?
This Portuguese study looks at pre- and postoperative peak nasal inspiratory flow (PNIF) in 72 consecutive patients undergoing septorhinoplasty surgery. The aim was to demonstrate the functional value of spreader graft insertion, the aesthetic value having already been confirmed. In...
Chronic rhinosinusitis and sleep
This is an interesting article from the Chung Shan Medical University in Taiwan. One-hundred-and-thirty-nine patients were enrolled into this five-year study. They all had chronic rhinosinusitis with or without polyposis and underwent sinus surgery. The aim was to investigate a...
