You searched for "genes"
Philosophy and reality of entrepreneurship
Before you take the time to read this article, be informed that it is indeed hard to be an entrepreneur. It warrants passion, sacrifice, total commitment and willingness to spend day and night (even in your sleep) thinking and working...HPV and ENT; should we vaccinate boys?
David Black and Charlie Hall reiterate Vin Paleri’s pleas for a common sense evidence-based approach by those who allocate healthcare resources to the now urgent issue of HPV-related disease. They discuss the merits of different vaccines and the need for...KTP laser in the office
KTP laser surgery offers a new way of selectively targeting microvasculature within laryngeal lesions and leaving normal surrounding tissues like epithelium and lamina propria intact – and thus preserving physiological phonation. This kind of selective photoangiolysis can be performed in...Ronald G Macbeth – the instigator of BACO
The structure of BACO has changed dramatically since the first conference in 1963, but the fundamental elements of academic excellence, instructional sessions and social events have been common threads. Andrew Freeland, who worked with Ronald Macbeth, the instigator of BACO,...
Novel wax solvent
This paper describes an open label, prospective study undertaken by the authors to demonstrate the safety and efficacy of a novel topical wax solvent. This new product has a dual action using a bicarbonate system to disrupt the esters and...
Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy
Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...
A drug to prevent hearing loss caused by ototoxic therapeutics
This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...
Bile acids and pharyngeal malignancy
Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...
The evidence for various treatments of autoimmune ear disease
The difficulty with this disease entity is that it is a heterogeneous group of conditions affecting the ear and a widely accepted diagnostic criteria does not exist. It is therefore difficult to conduct a well controlled trial and this systematic...
New aminoglycosides with reduced ototoxicity risk
Aminoglycoside antibiotics are widely used for infections affecting patients of all ages and at different sites, however they carry a risk of ototoxicity, nephrotoxicity and rarely peripheral neuropathy. Preventing ototoxicity is crucial to the maintenance of auditory function and quality...
Preoperative tumour embolisation
This review article analyses the role of preoperative endovascular tumour embolisation in the treatment of a variety of hypervascular head and neck lesions including juvenile nasal angiofibroma, glomus tumour, carotid body tumours, and meningioma. Although the concept of tumour embolisation...
