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CRSwNP, another monoclonal antibody
Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...Old age is hard to swallow
This article takes us through the diagnosis and management of swallowing problems common in older age. As our global population continues to grow and live longer, dysphagia will continue to be a global problem which needs to be recognised, understood...What you need to know about recent advances in genetics of hearing loss in the newborn
Identifying the underlying genetic cause of hearing loss in newborns can improve dramatically the early diagnosis and appropriate intervention. Hearing loss is the most common sensory disorder at birth, affecting approximately two out of 1000 newborns [1]. Congenital impaired hearing...Scientific advances in mapping syndromic hearing loss
From more than 22000 genes that we humans have, approximately 3000 genes are associated with human communication. There are tens of syndromes which have been identified to be accompanied by hearing loss. Disorders of almost every organ of the body...
Passive smoking and rhinosinusitis
One would expect that subjects exposed to more passive smoke would have a significantly increased level of rhinosinusitis. This study looked at a reasonable number of sinusitis and control subjects (404 and 165) using hair nicotine as an assessment of...
Laryngeal Function and Voice Disorders
This is a detailed, 323-page resource covering laryngeal function and voice disorders, basic science and clinical assessment. Spanning nine chapters, the authors cover the anatomy and physiology of phonation, survey of voice disorders, voice diagnostics, acoustic analysis, aerodynamic analyses, endoscopy...
Does head trauma as aetiology of deafness affect the outcomes of cochlear implantation?
Head trauma associated with temporal bone fractures is a well known aetiological factor for deafness. The literature assessing the outcomes of cochlear implantation in such cases is rather limited. In this paper, the authors compared the performance of implantees with...
Leptin has no role in idiopathic sudden sensorineural hearing loss
This paper from Turkey claims to be the first study dealing with the relationship between leptin and idiopathic sudden sensorineural hearing loss (ISSHL). I remember leptin being a fashionable topic in obesity research, when leptin deficiency was thought to be...Sleep apnoea in children with craniofacial syndromes
Whilst snoring and obstructive sleep apnoea are relatively common diagnoses in paediatric ENT, children with craniofacial syndromes take the problem to the next level. Robert Nash and Michelle Wyatt describe the Great Ormond Street multidisciplinary approach to treating this complex...Making audiology work during COVID-19 and beyond
‘New normal’ is another phrase that has become synonymous with this pandemic. In this article, consideration for ‘low-touch’ and ‘no touch’ audiological pathways are described for adoption as the ‘new normal’ for hearing healthcare. The COVID-19 crisis has ushered in...
Cobalt hip implants and auditory-vestibular outcome
Cobalt-chromium (Co-Cr), metal-to-metal hip implants were commonly used until several side-effects were reported due to an increased level of Co and Cr metal ions in patients’ blood. Although this type of hip replacement was almost completely abandoned, there are still...
