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CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...
Office-based intralesional corticosteroids injections for subglottic stenosis. Is it effective?
Subglottic and proximal tracheal stenosis in adults has three main aetiologies: (a) prolonged endotracheal intubation; (b) idiopathic; (C) rheumatologic related. Endoscopic dilation is the mainstay treatment strategy for subglottic and proximal tracheal stenosis. Its major limitation is restenosis requiring repeated...
Applying ‘Sal classification’ to parotid cytology to replicate the success of the Thy classification system
The usefulness of the Thy classification in thyroid gland disease has led to attempts to generate a similar cytology classification for parotid lesions. However, the accuracy of fine-needle aspiration cytology in salivary gland disease is more variable because of the...
Technique for benign tumours in the tail of the parotid gland
This is a retrospective study of 89 patients from China, 49 of whom were treated surgically by a partial superficial parotidectomy through retrograde approach, and 40 treated as an extracapsular dissection for benign tumours of the tail of the parotid...
IL-25 and nasal polyps, another target
Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...
Bile acids and pharyngeal malignancy
Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...
Precision medicine in allergic rhinitis and chronic rhinosinusitis
Precision medicine (PM) with its ‘four Ps’ (personalised, predictive, preventive and participatory) is about appreciating differences between individuals when offering management options for health problems. Multiple groups interested in rhinology such as EPOS and ARIA supported a review of the...
Management of stage IV pharyngolaryngeal lesions
This is a retrospective study of 63 patients presenting with stage four laryngeal and/or hypopharyngeal squamous cell carcinoma. The aim was to define the factors influencing the oncological and functional outcomes of the patients. All patients had T4 lesions with...
Single sided deafness and cochlear implants
Cochlear implants (CI) can restore hearing in the profoundly deaf ear. Risk/ benefit and cost considerations dictate strict criteria that must be met for patients to be eligible. People with single-sided deafness are not eligible to receive a cochlear implant...
Audiology Practice Management
Brian J Taylor manages to skilfully compile a plethora of information relating to all aspects of audiology practice management. The author has cleverly formulated this book into bite-sized chunks which are easy to read, understand and follow. This book is...
RadCases Head and Neck Imaging
This is one of a series of books published by Thieme which are written for trainees in radiology. The depth and breadth would suit a higher-level trainee with an interest in head and neck imaging coming up to exit examinations...
