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Wandering foreign bodies in the upper aerodigestive tract

Fish and chicken bones, along with metal wires, are among the most commonly ingested foreign bodies. Due to their linear shape and sharp edges, they can sometimes migrate beyond the lumen, making conventional endoscopic extraction unsuccessful. This issue is further...

Early recognition aiding better prognosis?

As we are all aware, acute invasive fungal rhinosinusitis (AIFR) is a life-threatening disease which typically affects immunocompromised patients. It is diagnosed via typical signs, symptoms and presentation but gold standard is by biopsy of tissues demonstrating infiltration fungal hyphae....

Benefits of bilateral cochlear implants

In an ideal world, if you could increase the clinical use of bilateral cochlear implant (CI) treatment, would you? If you’re interested in exploring the clinical benefits of bilateral CIs, or how reviews can directly inform patient care, this systematic...

Paediatrics Issue I

To skip directly to features, click the links below: Welcome from the editor - by Prof Ray Clarke and Claire Benton Industry News Setting up a paediatric ORL service with limited resources - by Raman Eswaran Engaging adolescents in hearing...

MedShr for ENT and audiology: clinical case discussion on the go

The COVID-19 pandemic has changed all aspects of our lives – not least medical education. With isolation being the buzzword at the moment, the internet and social media are popular sources for official and crowd-sourced content. In this article, Samantha...

Vestibular Testing Interpretation: Drill and Practice

My overall impression of this book is that I liked it. While it reports to be designed for a trainee or junior practitioner, it may be useful for clinicians for whom vestibular conditions and testing is an area of heart-sink...

Team proves secure pathway to the inner ear

An international team of surgeons and scientists has, for the first time, validated safe surgical access to the central core of the human cochlea.

Targeting the microbiome in chronic rhinosinusitis

Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...

Hyposalivation: a review of current and future treatments

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Eosinophilic or not eosinophilic: dupilumab seems to work

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...

What’s hidden in hidden hearing loss?

In order to truly understand the many key aspects of acquired sensorineural hearing loss, the role of cochlear synaptopathy or ‘hidden hearing loss’ must be considered. Dan Guo and Sharon Kujawa review and summarise what we know to date, including...