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Transtympanic plugging for chronic patulous eustachian tube

The authors developed a silicone plug (Kobayashi plug) to manage severe intractable patulous eustachian tube dysfunction (PET). This retrospective study investigates ET function after Kobayashi plug surgery, based on postoperative tympanic membrane (TM) findings and active opening (AO) of the...

A systematic review of adjunctive probiotic therapy in the management of chronic rhinosinusitis

It is generally understood that administering substances containing live microbiologically active micro-organisms (probiotics) enhances the treatment of chronic rhinosinusitis. Probiotics manipulate and rebalance the alterations occurring in the local microbiome in chronic rhinosinusitis patients. This results in propagation of healthy...

Wandering foreign bodies in the upper aerodigestive tract

Fish and chicken bones, along with metal wires, are among the most commonly ingested foreign bodies. Due to their linear shape and sharp edges, they can sometimes migrate beyond the lumen, making conventional endoscopic extraction unsuccessful. This issue is further...

Early recognition aiding better prognosis?

As we are all aware, acute invasive fungal rhinosinusitis (AIFR) is a life-threatening disease which typically affects immunocompromised patients. It is diagnosed via typical signs, symptoms and presentation but gold standard is by biopsy of tissues demonstrating infiltration fungal hyphae....

Benefits of bilateral cochlear implants

In an ideal world, if you could increase the clinical use of bilateral cochlear implant (CI) treatment, would you? If you’re interested in exploring the clinical benefits of bilateral CIs, or how reviews can directly inform patient care, this systematic...

Paediatrics Issue I

To skip directly to features, click the links below: Welcome from the editor - by Prof Ray Clarke and Claire Benton Industry News Setting up a paediatric ORL service with limited resources - by Raman Eswaran Engaging adolescents in hearing...

Team proves secure pathway to the inner ear

An international team of surgeons and scientists has, for the first time, validated safe surgical access to the central core of the human cochlea.

Balance Disorders: A Brief Overview

Managing balance patients poses a challenge for many clinicians. Vestibular disorders affect a large part of the population and hence present to various specialties including ENT, audiology, neurology and primary care. The healthcare cost of balance disorders and any resultant...

Targeting the microbiome in chronic rhinosinusitis

Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...

Hyposalivation: a review of current and future treatments

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

What’s hidden in hidden hearing loss?

In order to truly understand the many key aspects of acquired sensorineural hearing loss, the role of cochlear synaptopathy or ‘hidden hearing loss’ must be considered. Dan Guo and Sharon Kujawa review and summarise what we know to date, including...

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...