Search

Intratympanic steroids in Ménière's disease: what’s the evidence?

The days of drastic surgery for Ménière's disease are long gone. We know that intratympanic injections can deliver high doses of medication to the inner ear with minimal discomfort and minimal risk. But how do we choose from the myriad...

Tinnitus treatment device from concept to commercialisation

Innovation in the field of healthcare is fraught with nearly insurmountable challenges. Bringing a novel product to the market requires a new (patentable) idea that can be reduced to practice, manufactured at scale, and can pass all regulatory barriers. In...

Hyperacusis and autism spectrum disorder

Several different auditory deficits have been found to be co-morbidities of ASD. This article reviews literature with respect to the relationship between hyperacusis and ASD. Autism spectrum disorder (ASD) can be characterised as a neurodevelopmental condition that is marked by...

Role of interventional neuroradiology in otorhinolarygological pathology 
– a brief review

Introduction Since its advent in 1964 when Dotter percutaneously dilated a stenosed femoral artery [1], interventional radiology has undergone tremendous advancement in both imaging and devices that have enabled the operator (interventional radiologist) to access very distal small vasculature and...

Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm

Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...

Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

The effects of polypharmacy in the elderly

Another pill to cure the ill? Alec Lapira discusses the warning signs of polypharmacy in the elderly population. Polypharmacy in the elderly Polypharmacy – defined as the use of five or more medications – occurs in 20–37% of older people...

Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

Smart cochlear device: how biosensors could revolutionise hearing care

Smart cochlear implants could monitor inner ear health, deliver drugs and adapt in real time, merging biosensing, microfluidics and personalised hearing care. From passive hearing aids to smart implants Hearing technology has advanced dramatically over the last few decades, yet...

Genomic testing for deafness and its implications

Gene therapies for hearing loss are rapidly advancing and will be transitioning to clinical practice. Here, the authors explain why clinicians involved in managing these disorders need to be aware of these advances. Genomic testing in England was significantly reconfigured...