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OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...
Cochlear implantation in SSD
There are currently several trials for cochlear implantation (CI) in single-sided deafness (SSD) being undertaken to answer some of the questions this paper from New York raises. Who is best suited to receive one? What are their outcomes and how...
Chemo-radiation in elderly patients with head and neck cancers
Chemo-radiotherapy is the standard of care for organ preservation in stage three and four oropharyngeal cancer, prospective data on patients over 65 has not been available as they are usually excluded from randomised trials. This paper reviews the experience of...
Is it really working? Assessment versus real-life language measures
Research in the field of language treatment and rehabilitation to date has used single-word naming as a controlled measure of outcome. Yet, given people do not actually communicate in single words, there is much debate as to whether this approach...Management of single-sided deafness in adults: a bone conduction solution
Single-sided deafness (SSD) presents a limited number of methods for management, and not all of them meet the patient’s expectations. The aim of this article is to set out the available bone-conduction treatment methods for managing single‑sided deafness in adults....Quick & Efficient Procedures with DTR’s Sterile Single-use Aural Care Range of Instruments
DTR Medical’s Single-use Aural Care Instruments have been carefully designed to assist in the restoration of hearing through a Hearing Aid when the mechanism becomes sclerosed or fused together.
Case study suggesting mtDNA mutation as a tinnitus factor: ND1:m.3394T>C
Konadath et al report a genetic case study of a 24-year-old female experiencing reduced hearing sensitivity and tinnitus along with a blocked sensation in her right ear, sudden onset one year prior with no other otological complaints. Standard audiometry along...Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically
While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.Reducing hierarchy for individuals and teams across ENT
Alexander Pope said that “to err is human”, but medical errors can have serious consequences. How can better communication minimise the risk of them occurring in the first place? Allowing all members of the surgical team to feel empowered to...
Application of balloon dilatation in chronic eustachian tube dysfunction
Chronic eustachian tube dysfunction prevails in 1% of the adult population and can predispose to middle ear disease. There are subjective and objective features of this condition that can affect quality of life. The common methods to treat eustachian tube...
Predicting outcomes in rhinology using fluid dynamic models
This article discusses the rhinological applications of computational fluid dynamics (CFD) – a method derived from engineering applications, such as aerodynamics. Its appeal is that it can provide simulated data on airflow velocity, pressure, resistance, temperature, humidity, heat flux and...
