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Does pollution worsen inflammatory nasal problems?
This ambitious study, conducted over a period of four years, assessed 27,863 patients and compared levels of allergic rhinitis (AR) or chronic rhinosinusitis (CRS) with the levels of air pollution recorded, as assessed by levels of particulate matter (PM10). They...
Is there an association with cognitive impairment and hearing loss in a developing country?
Hearing loss (HL) is the third leading chronic health condition among older adults. Most studies investigating HL and cognition have been performed in high-income countries. Risk factors for dementia (eg. hypertension, midlife hearing loss, obesity and physical inactivity) are more...The European TINNET COST Action BM1306
Winfried Schlee describes how a major European funding award is bringing together experts who are committed to collectively developing a better understanding of tinnitus. This work is vital if we are to pioneer effective treatments for the condition in its...The search for pharmacological treatments for hearing loss and tinnitus
Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...
Simple preoperative tests predicting outcomes for ESS patients?
We are all familiar with patients suffering extensive nasal polyps who relapse all to soon after careful and thorough endoscopic sinus surgery (ESS). This paper looks to answer whether we can predict which patients will do well, and which less...
Surgical outcomes of myringoplasty using platelet-rich plasma
Tympanic membrane (TM) perforations can affect people’s quality of life due to recurrent infections. Management is often by surgical repair. In this study, the authors investigated the outcomes of a minimally invasive approach of patch myringoplasty using an atelocollagen sponge...
Updates on current evidence for biologics in chronic rhinosinusitis
For a comparatively short piece, this article manages to pack in a lot of important information about a complex emerging area of rhinology – immunologically targeted therapy (biologics). Immunologically targeted therapy is a rapidly progressing and expanding domain which is...
The polyp shrinker
Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...
The effects of paediatric tracheostomy
Paediatric tracheostomy is usually an essential procedure to preserve life, or to allow a patient to function in the community. However, the effect of tracheostomy on the developing child - care requirements, lack of voice, impaired swallow, constant risk of...
Tell me like it is: advice for relatives of people with aphasia
More than a quarter of people who have a stroke present with aphasia immediately post-stroke (approx. 30%) and of these, around 60% experience chronic communication difficulties. Provision of information is seen as one of the top 10 best practice recommendations...
What are the risk factors for new onset tinnitus?
Factors associated with tinnitus have mainly been studied cross-sectionally. Tinnitus is associated with hearing loss, noise exposure, ototoxic medication, head and neck trauma, smoking and depression and anxiety. Only a few studies exist that report on risk factors for developing...
