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Assessment of genetic disorders: congenital sensorineural hearing loss

Severe or profound sensorineural hearing impairment (SNHI) is a common birth defect, affecting approximately 1 in 1000 newborns [1]. SNHI may result from environmental causes or have a genetic basis. The genetic causes can be further subdivided into non-syndromic (isolated...

Scientific advances in mapping syndromic hearing loss

From more than 22000 genes that we humans have, approximately 3000 genes are associated with human communication. There are tens of syndromes which have been identified to be accompanied by hearing loss. Disorders of almost every organ of the body...

The impact of hearing loss in children with Down syndrome

Hearing loss and language development Down syndrome (DS) usually arises due to trisomy 21 and is associated with intellectual disability and risks of developmental delays and difficulties, including hearing loss. Hearing loss is common in children with DS [1]. In...

Detecting hearing loss in the military: are the current methods adequate?

A team at the University of Southampton have been funded by the Ministry of Defence to investigate how to improve the assessment of auditory fitness for duty in the UK Armed Forces. Matt Blyth talks us through the current methods...

The search for pharmacological treatments for hearing loss and tinnitus

Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...

What’s hidden in hidden hearing loss?

In order to truly understand the many key aspects of acquired sensorineural hearing loss, the role of cochlear synaptopathy or ‘hidden hearing loss’ must be considered. Dan Guo and Sharon Kujawa review and summarise what we know to date, including...

Otoacoustic emissions in the diagnostic test battery for hearing loss

So, they are great for screening, but how can otoacoustic emissions be integrated into the diagnostic test battery? Beth Prieve examines the role of diagnostic OAEs by asking three simple questions. Audiologists and otolaryngologists are familiar with otoacoustic emissions (OAEs)...

Lessons from the outcomes of children with hearing loss study

The Outcomes of Children with Hearing Loss (OCHL) study of 300 children with hearing loss has targeted several factors that are under the control of audiologists and parents. Drs McCreery and Walker discuss how these ‘lessons learned’ can lead to...

The importance of hearing aid validation in infants with hearing loss

Hearing aid validation requires that speech discrimination be measured, yet there are no validated methods of measuring speech discrimination in infants and toddlers. Prof Uhler describes two related approaches that are showing promise. Speech discrimination is the gold standard for...

MDT clinics for adults with learning disabilities and hearing loss

Healthcare providers can have limitations and challenges providing optimum care for patients with intellectual disabilities. Siobhan Brennan and Susanna Goodhart highlight key professionals and carers who may be instrumental when trying to deliver good management and care along with other...

Hearing loss and cognition: something to think about

Irace, Chern and Golub propose causal and non-causal mechanisms for the links between hearing loss and dementia, concluding with a discussion of several proactive measures available to help preserve neurocognitive health in older adults with hearing loss. What is age-related...

COOL therapy for cisplatin-induced hearing loss

Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...