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Active smoking predicts poor outcome in HPV positive oropharyngeal squamous cell carcinoma
Tobacco smoking is a well-known risk factor in human papilloma virus (HPV)-negative head and neck squamous cell cancer. Its effects include increased risk of treatment failure, distant metastases and reduced overall survival. HPV has been increasingly implicated as a causative...
Are we screening enough? Genetics in adult-onset sensorineural hearing loss
Sensorineural hearing loss (SNHL) in adults can be a result of multiple factors such as age, noise exposure and autoimmune pathology. In a group of patients, no cause is identified and the SNHL is treated as idiopathic. Authors evaluate the...
A trial of house dust mite sublingual tablet in children with allergic rhinitis
The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...Chester-gel technique
Umesh Nagalotimath and Robert Temple describe a simple and effective technique for enhancing vision during endosheath use for flexible nasendoscopy. Endosheaths are used to complement the cleaning of flexible scopes. The advantages are time saving for clinicians as this reduces...Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry
We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...Embracing the changes prompted by lockdown
March 2020 introduced the concept of lockdown to audiology services in the NHS, prompting a rethink of how to best provide hearing care. In this issue, we hear from Hanna Jeffery, a Clinical Scientist working at the Royal Glamorgan Hospital...Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours
Introduction Cancer cases continue to increase worldwide, and head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...The BICYCLE Project
It has been four years since the Covid pandemic forced people to stay at home. Many families had children during this period and these babies experienced social restrictions during the first year of life, a critical time for their development....
