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Subjective tinnitus – adding mutebutton™ to your tinnitus toolbox
Neurophysiologic tinnitus or subjective tinnitus is typically a sound or a number of sounds that originate from the auditory nervous system. They are unwanted sounds that do not exist in the external environment. They can be heard in one or...Minimally invasive techniques for benign salivary gland obstruction
Salivary gland obstruction is a common condition – it is recognised by a complaint of intermittent meal-time swelling of the affected salivary gland and can be accompanied by recurrent infections. Imaging can identify the nature and location of an obstruction...
Maxillary osteotomy stability
This systematic review assesses inferior repositioning of the maxilla six months after surgery. Two articles were identified with a total of 22 patients. The repositioning was of a mean of 3.2 to 4.5mm anteriorly and 0.1 to 1.8mm posteriorly. Six...
Dupilumab prospective RCT for CRSwNP, a multinational trial of 60 patients with a 16-week CT follow-up
This transcontinental work describes a randomised, double blind, placebo controlled parallel group study over a 16-week period, assessing 60 patients with CRSwNP by CT scan scores. All patients had a four-week period of intranasal corticosteroids followed by randomisation to add...
Lost and sound: exploring hyperbaric oxygen therapy for refractory SSNHL
Can hyperbaric oxygen therapy (HBOT) offer a breakthrough for patients with refractory sudden sensorineural hearing loss (SSNHL)? SSNHL is defined as acute hearing loss of ≥30 decibels in three consecutive frequencies within three days. Typically, it’s treated with two weeks...
Bevacizumab, NF2, hearing and age
Introduction NF2-related schwannomatosis (NF2-SWN) is an autosomal dominant disorder leading to the development of schwannomas, meningiomas and spinal cord ependymomas. Younger age is a negative prognostic factor. Treatment includes observation, surgery, radiotherapy and medical therapy with bevacizumab (VEGF monoclonal antibody)....
Drug eluting stent vs INCS for CRS
A prospective, randomised study from Finland to compare a drug eluting stent (DES) and intranasal corticosteroids (INCS) in 63 patients as assessed by SNOT-22, VAS, endoscopy, CT and rhinometry pre-treatment, at three and six months post treatment. Recruitment was over...
Outcomes of office-based biopsies for laryngopharyngeal carcinoma – faster diagnoses and equivalent oncological outcomes as compared to biopsies under general anaesthesia
Patients in the UK with head and neck cancers are the most likely to face long waits to treatment in comparison to other cancer sites, with only just over half commencing treatment within 62 days of being referred on a...
Dysplasia at the margins of laryngeal cancer specimens following laser resection – is conservative management appropriate?
Transoral laser microsurgery (TOLM) remains the cornerstone of treatment for early laryngeal squamous cell carcinomas. Whilst the hope is always to achieve a complete surgical excision with clear margins, it is sometimes the case that on histological analysis, disease is...
SPECT scans not justified in growth of the mandibular condyle
This is a paper from Hong Kong of 200 patients between January 2011 and July 2013 who underwent SPECT bone scintigraphy for assessment of growth causing condylar hyperplasia and subsequent mandibular asymmetry. Thirty-four patients were found to have active growth...
Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer
The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...
