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Dupilumab prospective RCT for CRSwNP, a multinational trial of 60 patients with a 16-week CT follow-up
This transcontinental work describes a randomised, double blind, placebo controlled parallel group study over a 16-week period, assessing 60 patients with CRSwNP by CT scan scores. All patients had a four-week period of intranasal corticosteroids followed by randomisation to add...
Lost and sound: exploring hyperbaric oxygen therapy for refractory SSNHL
Can hyperbaric oxygen therapy (HBOT) offer a breakthrough for patients with refractory sudden sensorineural hearing loss (SSNHL)? SSNHL is defined as acute hearing loss of ≥30 decibels in three consecutive frequencies within three days. Typically, it’s treated with two weeks...
Drug eluting stent vs INCS for CRS
A prospective, randomised study from Finland to compare a drug eluting stent (DES) and intranasal corticosteroids (INCS) in 63 patients as assessed by SNOT-22, VAS, endoscopy, CT and rhinometry pre-treatment, at three and six months post treatment. Recruitment was over...
Outcomes of office-based biopsies for laryngopharyngeal carcinoma – faster diagnoses and equivalent oncological outcomes as compared to biopsies under general anaesthesia
Patients in the UK with head and neck cancers are the most likely to face long waits to treatment in comparison to other cancer sites, with only just over half commencing treatment within 62 days of being referred on a...
Dysplasia at the margins of laryngeal cancer specimens following laser resection – is conservative management appropriate?
Transoral laser microsurgery (TOLM) remains the cornerstone of treatment for early laryngeal squamous cell carcinomas. Whilst the hope is always to achieve a complete surgical excision with clear margins, it is sometimes the case that on histological analysis, disease is...
SPECT scans not justified in growth of the mandibular condyle
This is a paper from Hong Kong of 200 patients between January 2011 and July 2013 who underwent SPECT bone scintigraphy for assessment of growth causing condylar hyperplasia and subsequent mandibular asymmetry. Thirty-four patients were found to have active growth...
Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer
The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...Absorbing the hurt
In this article, taken from his blog, ENT surgeon John McGarva reminds us that while we can’t fix everything, we may still be able to help. It was a long time ago. I was a scarily young Houseman, barely 22,...Functional Endoscopic Sinus Surgery (FESS) - Part 1
In the first of a two-part series, Martyn Barnes and colleagues discuss indications for functional endoscopic sinus surgery (FESS), the surgical objectives and techniques, patient expectations and the risks of surgery. In part two, the authors will discuss how to...
Radiosurgery for large vestibular schwannomas
The authors conducted a retrospective study of patients with large Koos grade 4 vestibular schwannomas undergoing gamma knife radiosurgery. A total of 68 patients with tumour size greater than 4 cm3 with baseline serviceable 60% hearing who received 12 Gray...DP Medical brings groundbreaking non-occlusive airway dilation balloon to UK market
Leading healthcare supplies company, DP Medical Systems Ltd, is bringing a groundbreaking, non-occlusive airway dilation balloon to the UK market.
