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Novel wax solvent
This paper describes an open label, prospective study undertaken by the authors to demonstrate the safety and efficacy of a novel topical wax solvent. This new product has a dual action using a bicarbonate system to disrupt the esters and...
Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy
Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...
A drug to prevent hearing loss caused by ototoxic therapeutics
This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...
The evidence for various treatments of autoimmune ear disease
The difficulty with this disease entity is that it is a heterogeneous group of conditions affecting the ear and a widely accepted diagnostic criteria does not exist. It is therefore difficult to conduct a well controlled trial and this systematic...
