You searched for "genes"

890 results found

Gastro-oesophageal reflux and cricopharyngeal dysfunction – how do they link?

It has been hypothesised that cricopharyngeal muscle hypertrophy develops as a response to chronic gastro-oesophageal reflux disease. The cricopharyngeus muscle is an important component and contributor to the upper oesophageal sphincter that creates a barrier between the pharynx and oesophagus....

Association of diabetes mellitus type 2 with age-related changes in the larynx

Diabetes affects the body with changes in the neurological, muscular and vascular systems. It is therefore conceivable that the larynx, which is a musculoskeletal organ, can be adversely affected by type 2 diabetes mellitus. To explore this possibility, 174 Caucasian...

An unrecognised anatomical variant which may help frontal sinus surgery

Anatomic variants in the frontal sinus have significant implications in endoscopic sinus surgery. In this illustrative study, the authors describe a newly-observed anatomical variant – a mucosa lined prism‑shaped space between the most superior part of the nasal septum and...

Obstructive sleep apnoea: Does maxillomandibular advancement work?

This is a paper from the Netherlands reviewing 62 patients who underwent maxillomandibular advancement for moderate to severe obstructive sleep apnoea. The authors observed a 71% success rate with mean apnoea hypopnea index (AHI) reduction of 69%. There was no...

How does the Dizziness Handicap Inventory (DHI) correlate with demographics and symptoms of patients?

The DHI is widely used to assess the self-perceived emotional, functional and physical disability in subjects with dizziness and balance problems. By studying the data of 568 patients retrospectively, the authors sought to determine the gender and age differences in...

Sellar surgery – when to prepare for repair

Endoscopic sellar surgery, especially for adenomas, is a relatively safe, straightforward surgery with (mostly) reproducible results and few complications. One of the commonest complications is the creation of a CSF leak with the subsequent need for repair (there is usually...

Does ‘weekend effect’ alter post tonsillectomy haemorrhage rates?

Staffing levels are generally low over the weekends and senior physicians are less easily available. It is generally believed that this affects patients undergoing high-risk surgery. Whether doing tonsillectomy at weekends adds to the risks of post tonsillectomy haemorrhage is...

Does trainee participation in cochlear implant surgery affect operative times?

The role of surgical education is a very sensitive issue in spite of the obvious need and the obligation of doctors to pass on their knowledge and experience to the next generation. This study is very interesting as it assesses...

Healthcare Disparities in Otolaryngology

The topic of this book seems timely given the increasing focus in recent years on equality and prevention of discrimination. But my initial reaction was, do we need a 300-page textbook on this topic? Is there so much to say?...

Recovery rates in sudden sensorineural hearing loss

Sudden sensorineural hearing loss (SSNHL) is most commonly idiopathic, and is seen relatively frequently in ENT practice. Recovery spans a period of around 1-2 months, and ultimate outcomes are highly variable, from complete recovery to no detectable hearing. Although the...

Assessment of the incidence of LPR in the Greek population using the Reflux Symptom Index

Using the self-administered nine-item Belafsky Reflux Symptom Index (RSI) questionnaire, the authors of this article assessed the prevalence of laryngopharyngeal reflux (LPR) in the general adult Greek population as well as predisposing and associated factors for developing LPR. They found...

Impact of Covid-19 on secretory otitis media (SOM) in terms of rate of intervention, effusion detected intraoperatively and seasonal variation

It is widely known that secretory otitis media (SOM) has seasonal variations. In well-judged cases, there is middle ear effusion found at the time of surgery. In this retrospective study, the authors have tried to assess if Covid-19 changed these...