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eNOS and OME

The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

Direct your patients to Life On The Level!

Life On The level, a voluntary Balance Condition Support Group celebrates over five years of helping sufferers of all types of balance conditions, living anywhere in the world.

Is GERD linked to CRS?

We are all well aware that both chronic rhinosinusitis and reflux are prevalent in our populations. This meta-analysis looked at 25 studies investigating the association between GERD, LPR and CRS, therefore evaluating more than 117,000 patients. The results are fascinating...

Risk factors for post laryngectomy fistula

This is a meta-analysis looking at the postoperative pharyngocutaneous fistula rates following total laryngectomy. The authors ended up with 34 studies with about 2500 patients. The most striking finding was that preoperative radiotherapy was a significant risk factor as well...

An effective treatment for post Covid-19 smell loss?

It is well understood that calcium levels in the nasal mucous affect the ability to smell, with higher levels having a negative impact, and some studies have shown increased calcium levels in patients suffering with Covid-19-related olfactory dysfunction. Calcium chelating...

Evidence for balloon eustachian tuboplasty

Balloon eustachian tuboplasty is an emerging intervention aimed at the management of eustachian tube dysfunction (ETD) and its sequelae. The authors acknowledge that ETD is a common but frequently ill-defined problem, with no well-established direct treatment. They performed a systematic...

The big ask – maintaining the entrepreneurial spirit in academic facial plastic surgery in the USA

en·tre·pre·neur, noun a person who organises and operates a business and who has qualities of leadership, initiative and innovation. In the United States, facial plastic surgery (FPS) services are divided among private and academic practices. The vast majority of academic...

Understanding new and emerging categories of hearing devices

The hearing device landscape is rapidly changing, and what should be given, to whom, and why, are questions that many hearing healthcare professionals are asking. Brent Edwards discusses these questions and how consumer characteristics may influence their choice. In 2016,...

Otorhinolaryngology training in Haiti: a call for accompaniment

Haiti is a small Caribbean country in which a group of freedom fighters successfully defied Napoleon and the French military. It has faced embargoes, economic isolation, political crises and devastating natural disasters since its independence. Its GDP is 0.01% of...

A diagnostic survey of dizziness

The prevalence of self-reported dizziness and that requiring medical consultation is remarkably high. Cardiac and neuropathic comorbidities, often associated with these patients confuse the diagnosis. In this multicentre study, the prevalence and characteristics of various diagnostic groups, for example, Benign...

A parent’s journey: beyond the diagnosis

Tamsin Coates lives in Wallesey, UK and talks about coming to terms with the difficulties and joys of having two deaf children. Here she explains about the early days and the impact of their diagnosis upon the family. Thinking back...