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735 results found

Interleukins, cilia and polyps

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...

More aggressive FESS for recalcitrant CRS is the key

This is an interesting paper assessing the effectiveness of endoscopic modified medial maxillectomy (MMM) in cases of recalcitrant chronic rhinosinusitis (CRS), (the technique was also used for tumours, cystic fibrosis, FB, odontogenic disease and AFS) in 551 patients. The technique...

Can obstructive snoring affect the snorer’s ears as well?

Patients with obstructive sleep apnoea (OSA) often show severe nasal obstruction, chronic sinusitis and/or a deficit of nasal mucociliary clearance with nasopharyngeal stagnation of secretions possibly predisposing to eustachian tube dysfunction (ETD). This clinical prospective study investigates ETD, nasal resistance...

Sleep before and after nasal polyposis surgery

This prospective French study looked at the change in nasal symptoms related to sleep, in a questionnaire before and after nasal polyposis surgery. Sixty-three patients who underwent endoscopic sinus surgery completed the DyNaChron questionnaire before, at six weeks and at...

Expanding horizons: from speech therapy to communication therapy for people with Parkinson’s disease

This article explores the perspective of people living with Parkinson’s disease before and after participating in speech treatment delivered by a speech and language therapist (SLT). Semi-structured interviews were conducted with 11 participants. These interviews were held face to face...

Inferior alveolar nerve recovery after ORIF fractured mandible

Mandibular fractures are quite common facial injuries, but aetiology varies with country and age. Common treatment options are open reduction and internal fixation via an intra-oral or extra-oral incision. Nerve injury or dysfunction is often seen preoperatively and may also...

Ego-resiliency and tinnitus

Adults with tinnitus are 2.5 more likely to suffer with depression and anxiety. Ego-resiliency is the ability of a person to adapt to change and cope in difficult situations. This study aimed to determine whether ego-resiliency is related to perceived...

How does the Dizziness Handicap Inventory (DHI) correlate with demographics and symptoms of patients?

The DHI is widely used to assess the self-perceived emotional, functional and physical disability in subjects with dizziness and balance problems. By studying the data of 568 patients retrospectively, the authors sought to determine the gender and age differences in...

Outcomes in endoscopic sinus surgery

This study assessed the effect of endoscopic sinus surgery with regard to olfactory function and nasal obstruction, in chronic rhinosinusitis (CRS) patients with, and without, nasal polyposis. One hundred and thirteen patients entered the study, and assessments were performed pre-...

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

Role of the insula and orbitofrontal cortex in tinnitus related distress

It is estimated that 5% of the population suffer from chronic tinnitus with 17% of those suffering emotional distress. The authors attempted to study the neural correlates of tinnitus-related distress using functional magnetic resonance imaging (fMRI) during an Emotional Stroop...

A review of endoscopic sinus surgery outcomes

This review discusses the outcome measures that may be considered in the assessment of patients with chronic rhinosinusitis (CRS) as well as the outcomes of endoscopic sinus surgery (ESS) published so far. The authors also discuss the role of peri-operative...