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eNOS and OME
The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...
What are the non-inflammatory causes of a conductive loss?
This retrospective study looked at patients with an intact tympanic membrane with non-inflammatory causes – i.e. otitis media and cholesteotoma. They document their findings based on exploratory tympanotomy. They operated depending on the findings with either a stapedectomy or a...
Multisystem pathology in refractory otitis media with effusion
Recurrent middle ear effusion is a common problem and so is rhinosinusitis with polyposis. It is not often thought that the problem could be linked to multisystem pathology, such as eosinophilic granulomatous with polyposis. Therefore, repeated grommet insertions and surgical...
Nasal decongestants don’t improve Eustachian tube function
Prescribing nasal steroids and decongestants. It’s something most of us do routinely, in an effort to reduce chronic middle ear effusion in an adult by trying to improve eustachian tube (ET) patency. This study used clever devices (tube manometry and...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
Do you know what aphasia is?
In 2001 a survey was conducted in a number of towns across the world, including Exeter in the UK, to identify the level of awareness and knowledge of aphasia in the community. Aphasia is difficulty in producing or understanding language...
Stuttering and bullying - everyone’s business
This article emphasises that bullying (distinct from teasing- the former being defined as repeated actions intended as harmful, compared to good-natured interactions enjoyed by everyone) is an issue that can impact significantly on a child or young person’s ability to...
The GP and the ear
General practitioners are the first members of the medical community to deal with ear problems. In this survey, 11 GPs examined 124 patients using a regular otoscope and a video-otoscope and reported their findings in a 10-item table. The same...
Outcomes following endoscopic vs. microscopic ossiculoplasty
Endoscopic ear surgery continues to increase in popularity with an expanding range of applications in otology. The variety of angled scopes allow for superior visualisation of the surgical field and difficult to reach areas. However, use of endoscopes reduce the...
Is endoscopic approach more precise in addressing failed ventilation system in chronic mucosal ear disease?
Chronic mucosal disease, as opposed to cholesteatoma, is more directly related to failure of the ventilation system involving three channels. Isthmus anticus and isthmus posticus are channels in front and behind the long process of the incus and there is...
Impact of Covid-19 on secretory otitis media (SOM) in terms of rate of intervention, effusion detected intraoperatively and seasonal variation
It is widely known that secretory otitis media (SOM) has seasonal variations. In well-judged cases, there is middle ear effusion found at the time of surgery. In this retrospective study, the authors have tried to assess if Covid-19 changed these...
