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Recalcitrant chronic rhinosinusitis: What to do next?

Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...

Implantation Otology & Inner Ear Therapeutics Issue I

To skip directly to features, click the links below: Welcome from the editor - by Prof Manohar Bance Industry News Genomic therapies for hearing loss - by Manohar Bance Cell-based therapies - by Jennifer Harre, Athanasia Warnecke, Hinrish Staecker, Eva...

In conversation: Cesare Piazza and Giuseppe Spriano

Declan Costello catches up with the presidents of two important meetings taking place in Italy in June 2023 to discuss the highlights.

SEQaBOO: SEQuencing a Baby for an Optimal Outcome

There are at least 15 countries now running genome sequencing projects. The team in Manchester, UK, and Boston, USA, share their SEQaBOO project. Abstract SEQaBOO (SEQuencing a Baby for an Optimal Outcome) will transform newborn hearing screening (NBHS) by bringing...

Laryngology: Otorhinolaryngology – head and neck surgery series

A comprehensive and up to date textbook covering both conventional and contemporary topics in laryngology, written by authors of international repute, within 345 pages. The 39 chapters are divided into eight sections working through basic knowledge, clinical assessment and diagnostics,...

Reza Band<sup>®</sup> UES Assist Device

Members of the ENT and Audiology News team spoke to Rose Henrichs, Solutiones Vobis and Nick Maris, CEO and President of Somna Therapeutics about the Reza Band device. Nick Maris. Rose Henrichs. What is your involvement in Reza Band? And...

The many uses of human amnion

Human amnion has historically been the focus of much myth and superstition. To be born with the ‘caul’ intact was considered lucky and the caul was often manufactured into clothing. In 1910 foetal membranes were first used in skin transplantation...

Smell training is also effective in older patients

Olfactory loss is a common problem with a significant impact on quality of life. It has been demonstrated that olfactory training (OT) improves olfactory function in younger patients, but this study focuses in on patients aged 45 years and older....

A bittersweet finding

This is an elegant study, documenting the role of, and activation of, nitrous oxide in chronic sinusitis. Bitter taste receptors (TR2) have recently been identified as novel ‘players’ in sinonasal innate immunity and in chronic rhinosinusitis. The receptors are triggered...

The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...

Contemporary UK experience of oropharyngeal transoral laser microsurgery

It is well recognised that the current emergence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) as a distinct disease entity requires a fresh look at standard treatment modalities that are based on chemoradiotherapy for stage III/IVa OPSCC. The Newcastle experience...

Systemic steroids for sensorineural hearing loss

This Japanese retrospective study looked at whether the dosage of prednisolone affects the response rate in patients with idiopathic sudden sensorineural hearing loss. The authors included a total of 159 patients over a 14-year period who were treated with 200mg/day...