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237 results found

Metformin, the magical solution!

Both noise-induced hearing loss (NIHL) and vestibular schwannomas (VSs) pose a challenge in terms of management. Metformin was suggested as a potential therapeutic drug for NIHL when the drug-target interaction data was investigated. Additionally, there are studies which demonstrate reduction...

Rehabilitation of single-sided deafness with cochlear implants

The relatively recent emergence of cochlear implantation as a potential means of restoring hearing to a deafened ear, in the presence of normal hearing in the other ear, has proved an exciting and yet surprising development. James Tysome explores the...

The future of inner ear drug delivery

The techniques for delivering drugs to the inner ear system are evolving. Jeffrey Harris considers the myths, the facts and the potential for drug delivery innovations and how they can improve tomorrow’s hearing outcomes. The inner ear’s delicate membranous structure,...

Vestibular schwannoma surgery and inner ear injuries

Iatrogenic inner ear injury during vestibular schwannoma (VS) surgery ranges between 20% and 30% in the literature. However, there is no up-to-date quantification of such injuries, hence this study. The authors conducted a US-multicentre database search looking for patients who...

Hearing preservation in cochlear implantation – an American cocktail

There has been an increase in hearing preservation cochlear implant (HPCI) surgery over the last decade. Both steroid and L-N-acetylcysteine (NAC) were used and investigated respectively in the past in HPCI surgery. Authors investigated the role of perioperative NAC and...

Cochlear implantation in inner ear schwannoma patients

Inner ear schwannomas (IES) are rare. Patients with IES tend to lose their hearing. Surgery is a treatment option, but it leads to complete loss of hearing. Other treatment options include stereotactic radiosurgery (SRS) and watchful waiting (WW). The authors...

Radiological diagnosis of mastoiditis in patients screened for acoustic neuroma

Magnetic resonance imaging is the ‘gold standard’ for screening patients suspected to have acoustic neuroma. Various abnormalities are picked up through this investigation, one of which, not uncommonly reported, is mastoiditis. This requires referral to otolaryngology and further evaluation. In...

Centralisation of care for acoustic tumour surgeries?

Several factors are responsible for readmission after acoustic tumour removal. The authors retrospectively studied the association between hospital, patient and insurance factors with the rate of readmission following acoustic tumour removal in the United States using the Nationwide Readmission Database...

Scoring system to predict hearing impairment following hemifacial spasm surgical treatment

The authors analysed brain stem auditory evoked potentials prospectively in 100 patients undergoing endoscopic microvascular decompression for management of hemifacial spasm over a period of two years. They then developed a scoring system based on electrophysiological events to predict the...

Outcomes after facial nerve preservation surgery for large vestibular schwannomas

Large vestibular schwannomas (Koos grade three or four) are traditionally treated by surgical resection. Gross total resection of such large tumours often results in facial nerve dysfunction. Hence facial nerve preservation surgery was introduced in which maximal surgical resection is...

The role of prediction and gain in tinnitus

Dr Will Sedley is a Clinical Academic Neurologist who has done groundbreaking work in the field of tinnitus mechanisms. Here, he introduces and explains the concepts of prediction and of gain as they relate to troublesome tinnitus. This article focuses...

What you need to know about recent advances in genetics of hearing loss in the newborn

Identifying the underlying genetic cause of hearing loss in newborns can improve dramatically the early diagnosis and appropriate intervention. Hearing loss is the most common sensory disorder at birth, affecting approximately two out of 1000 newborns [1]. Congenital impaired hearing...