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Contemporary UK experience of oropharyngeal transoral laser microsurgery
It is well recognised that the current emergence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) as a distinct disease entity requires a fresh look at standard treatment modalities that are based on chemoradiotherapy for stage III/IVa OPSCC. The Newcastle experience...
‘Close’ surgical margin in oral tongue redefined, 2.3mm is as good as 5mm
Gold standard treatment of squamous cell carcinoma (SCC) of the oral tongue remains surgical resection of the primary tumour with negative margins. The primary goal is the complete excision of the tumour with no residual cancer cells left behind. A...
Office-based intralesional corticosteroids injections for subglottic stenosis. Is it effective?
Subglottic and proximal tracheal stenosis in adults has three main aetiologies: (a) prolonged endotracheal intubation; (b) idiopathic; (C) rheumatologic related. Endoscopic dilation is the mainstay treatment strategy for subglottic and proximal tracheal stenosis. Its major limitation is restenosis requiring repeated...
Bell’s palsy incidence in Korean population
Bell’s palsy is an acute idiopathic paresis or paralysis of the peripheral facial nerve. It is the most common cause of facial nerve palsy with a reported incidence ranging from 11.5–55.3 per 100,000. The aetiology remains unclear. Several studies have...Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours
Introduction Cancer cases continue to increase worldwide, and head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...The search for pharmacological treatments for hearing loss and tinnitus
Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...
Significance of abnormal retropharyngeal nodes in head and neck cancer
Abnormal retropharyngeal lymph nodes (RLN) have prognostic relevance for patients with oral, oropharyngeal or nasopharyngeal squamous cell carcinoma (SCC). However, consensus on the evaluation and management of abnormal RLN in these patients is lacking. The authors of this paper provided...
Risk factors for loco regional recurrence for oral SCC
Over 250,000 cases of oral squamous cell carcinomas are diagnosed annually worldwide with 128,000 registered deaths. The authors of this study are from a single institution in Germany and have conducted a retrospective audit of 517 patients with oral SCC...
