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Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

In conversation with Bill Gibson, Richard Ramsden and Shakeel Saeed

The surgical aspect of cochlear implantation is both a joy and a challenge – which is why we love it! In this article, Simon Freeman draws on the wisdom of his three previous mentors, sharing pearls from some of the...

A binaural detection task that reveals deficits in listeners having ‘slight’ or ‘hidden’ hearing loss

The association of degraded binaural processing in adults with clinically defined ‘slight’ or ‘hidden’ high frequency hearing loss is of great interest to clinicians if it can be measured. Leslie R Bernstein and Constantine Trahiotis share their findings in measurements...

In conversation with Professor Janet Wilson

As she approaches her retirement from clinical practice, Professor Janet Wilson speaks to our Editor (and fellow laryngologist) Declan Costello about surgical training, research, diversity, literature and the future. You have had an immensely successful career in ENT – how...

Wireless accessories for hearing aid users: putting the ‘soul’ back into hearing – a case study

The following case study reports on the experiences of a hearing impaired National Health Service (NHS) patient who was given Bluetooth accessories as part of a study into their benefits when used with hearing aids [1]. The name of the...

Transnasal endoscopic choanal atresia surgery

Surgery is currently the only definitive treatment for congenital choanal atresia (CCA). There are various surgical approaches including transnasal, transeptal or transpalatal. The authors propose that the preferred option is transnasal endoscopic choanal atresia surgery (TECAS) and set out to...

In conversation with Professor Paul J Donald

Prof Paul J Donald has recently stepped down as Chairman of the ORL-HN Department at UC Davis in Sacramento and is winding down to retirement. In this interview with Prof Pat Bradley, Prof Donald explains some of the highlights of...

Screening for hearing aid fittings – an approach for primary care

Introduction The communication difficulties related to hearing loss can lead to ‘depression, social withdrawal and problems with employment and access to information sources’ [1]. Furthermore, unmanaged hearing loss is associated with dementia, a poorer quality of life, depression, anxiety and...

Pharma chameleon

One morning in September ’95, about a month into my first house job on the South Coast of England, I emerged from the ridiculously early ward round on the coronary care unit feeling a bit dazed and therefore headed off...

Does septoplasty improve smell?

This is a study from Barcelona on a very interesting topic: does septoplasty change sense of smell? The theory being that a deviated septum would prevent airflow to the olfactory region and once the anatomical obstruction has been relieved, that...

TIVA in FESS: a meta-analysis

This meta-analysis is from Rochester, New York, and aims to add more evidence for the use of TIVA in endoscopic sinus surgery (FESS) to arm rhinologists keen for a quick, bloodless FESS in the discussion with anaesthetists who prefer inhalation....

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...