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1652 results found

Eosinophilic complications during dupilumab therapy

Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...

A surgeon’s perspective on the challenges facing cochlear implantation in children

Cochlear implantation in children offers a different set of challenges and goals to adult practice. In this article, Iain Bruce, Professor of Paediatric Otolaryngology in Manchester, UK, explains some of the current clinical and research challenges in paediatric cochlear implantation,...

Trainee-led collaborative research and audit in ENT: where are we now?

In late 2015 INTEGRATE, the UK ENT Trainee Research Network, was formed. Since then, two national projects have been completed and INTEGRATE has grown into a larger, more structured organisation, with otology, head and neck and rhinology subcommittees working alongside...

Intratympanic treatments for subjective idiopathic tinnitus

Direct application of medication into the ear is long established, going back as far as written records. In the modern era, greater understanding of aural anatomy revealed that drugs instilled in the middle ear could potentially diffuse into the cochlea...

Time and Life Management for Medical Students and Residents

Time and life management is not normally a skill we are taught growing up. As we grow from being a child to an adult, it is inevitable that we become independent managers of our time and schedule. Most who end...

CSOM in Mwanza, Tanzania

This is a prospective, cross-sectional study involving 301 patients consisting of farmers, students and employed professionals attending an ENT clinic in Mwanza, Tanzania. Of the 301 patients, 13 were HIV positive; 37.9% had some degree of conductive / sensorineural /...

The importance of s-ABR in auditory disorders

S-ABR is a method of recording speech-evoked-potentials, but where does it fit in the clinical and research test battery? Here, the authors examine the opportunities for s-ABR. The integrity of the neural transmission of acoustic stimuli is evaluated by auditory...

Tone deafness and perfect pitch

If you think you are tone deaf, do not despair. Singing tuition should help but it is probably too late to hope to develop perfect pitch. Consultant otolaryngologist and keen musician, Chris Aldren, discusses the complex and fascinating subject of...

Medicine and Seamus Heaney

Seamus Heaney grew up in the 1940s. Infectious diseases – diphtheria, poliomyelitis, mumps, measles and rubella – were rife. Stepping Stones recalled talk among older neighbours of ‘a-waiting on’ when they were close to death. Aunts and uncles succumbed to...

In conversation with Muaaz Tarabichi

Guest Editor, Chris Coulson, speaks to Dr Muaaz Tarabichi, a pioneer of endoscopic ear surgery, about how he has seen the technique evolve during his career, what challenges early EES practitioners have faced and his predictions for the future of...

In conversation with Professor Wolfgang Pirsig

Professor Wolfgang Pirsig is a key figure in the field of ENT history and is known for his fascinating discoveries of ENT features in art and historical objects. He kindly agreed to be interviewed for this special history focus by...

FDA Approved Lenire Expands Number of US Clinics

Neuromod Devices, the medical technology company that developed tinnitus treatment device, Lenire, has partnered with an additional 24 new US clinics to address the significant demand for the FDA Approved tinnitus treatment device.