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Building sound: from Stonehenge to a Symphony Hall
Modern architecture can use scientific techniques to shape room acoustics and create great sounding places. Professor Trevor Cox discusses our ancestors’ understanding of the importance of building techniques to enhance acoustics from Stonehenge to a Symphony Hall. Going to an...
Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
Long-term results for dupilumab are very promising!
Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...
A useful adjuvant treatment for SNAC or IP
5-Fluorouracil (5FU) is a topical preparation used in the treatment of various dermatological, ocular and gynaecologic malignant and pre-malignant conditions, and this literature review looks at the efficacy of 5FU in treating inverted papilloma and sinonasal tumours. The authors cite...Scotland’s first UKAS accreditation for paediatric audiology
The United Kingdom Accreditation Service (UKAS) has granted Scotland’s first accreditation against the Improving Quality In Physiological Services (IQIPS) standard. The award was made to the Audiology Department at NHS Tayside and covers both adult and paediatric audiology services delivered at four hospitals in Dundee, Perth and Brechin.The common frontal sinusotomy (Lothrop) and chronic rhinosinusitis
As our understanding of the pathophysiology of CRS evolves, so do our treatment strategies. It is accepted that in many cases, the main role of surgery is to allow better penetration of topical therapies to the sinus cavities. What, then,...Superior semicircular canal dehiscence: transmastoid obliteration
Sometimes patients with dizziness turn out to have slightly more unusual causes of their problem. Thomas Milner and Georgios Kontorinis describe their technique for managing patients who have a diagnosis of superior canal dehiscence as an identified cause of their...The process of medical innovation
You’ve got an amazing idea for a new device. It is going to change how your speciality of surgery is practised. It will lead to better operative results and lower risks to patients – that’s amazing, can I see it?...
