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Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

Magnetic resonance imaging (MRI) head without general anesthesia in children

‘Physician heal thyself’: this biblical proverb has an increasing importance in modern healthcare systems, especially when we consider the rising incidence of physical and mental burnout amongst all staff. Musculoskeletal disorders are increasing – according to the Work-Related Musculoskeletal Disorders...

Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?

Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...

Epley manoeuvre angles

Posterior canal benign paroxysmal positional vertigo (PC-BPPV) is a common vestibular cause of dizziness regularly encountered in the outpatient clinic. The condition is often diagnosed with a positive Dix-Hallpike manoeuvre (DHM) – turning the patient’s head 45 degrees to the...

EBM Stats Calc: there’s a stat for that

Quantifying the value of a specific test or intervention for a patient is no easy feat. Even when the value of a given test or intervention has been established, there may be additional case-specific factors to consider that are not...

Communicating with patients in 
‘Plain English’

Physicians have long been accused of using unnecessarily complicated language and impenetrable jargon as a way of maintaining their status, prestige and high earnings-potential, bamboozling the public and excluding them from meaningful discussion as part of what George Bernard Shaw...

Thyroid ultrasound elastography: does nodule stiffness predict malignancy?

Approximately 50% of the general population has a thyroid nodule while 5-15% of these are malignant [1]. A major challenge, therefore, is how to detect the malignant nodules for appropriate, timely treatment and avoid unnecessary, costly investigations for the remainder....

Hidden genetic disorders in children that may present to the otolaryngologist

Background Among the many hundreds of children presenting to the otolaryngology clinic are a few whose symptoms are due to an underlying genetic condition. In most cases the underlying syndrome is obvious and has already been diagnosed, such as the...

Surgical management of sleep disordered breathing

Snoring and sleep-disordered breathing are often described as multi-level problems, and different surgical procedures are required to treat the various sites of airway narrowing and/or collapse. Jonathan Hobson gives us an eloquent run-through the various options available to the ENT...

International Federation of Head and Neck Oncologic Societies (IFHNOS): its programmes and impact on head and neck cancer worldwide

In the first article of this edition, we introduce IFHNOS, which has created a major impact on the landscape of head and neck cancer treatment and education over the past quarter of a century by offering a global platform amongst...

The role of macrolide antibiotics in chronic rhinosinusitis

The use of long-term antibiotics in the treatment of chronic rhinosinusitis is a contentious issue, not only because of the increasing problem with antibiotic resistance but also because of the potential cardiac risks, including sudden death. In this article, Anders...

Electronic nicotine delivery systems (e-cigarettes): what you need to know

As an aid to stopping smoking e-cigarettes may have a role, but they are heavily promoted by industry as a leisure pursuit and desirable fashion accessory. Sneh Biyani and Craig Derkay gives a thorough account of what we know about...