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A new era in the treatment of recalcitrant nasal polyps?

Chronic rhinosinusitis with nasal polyps (CRSwNP) can be difficult to treat effectively in patients with aggressive or recalcitrant disease. Omalizumab (Xolair) is a monoclonal anti-IgE antibody with proven benefits for patients with moderate/severe asthma and CRSwNP, but this study looks...

Serum biomarkers for CRSwNP

This cross-sectional comparative study looked at 50 patients with nasal polyps who, at the time of diagnosis, also had a blood test evaluating serum total IgE, IL-17 and Pentraxin-3. The study assesses whether these blood markers are useful in the...

Are there any benefits of postoperative antibiotics after endoscopic transsphenoidal surgery for pituitary tumours?

This prospective randomised double-blind multicentre study evaluated whether postoperative antibiotics resulted in improvement in sinonasal quality of life (QoL) compared to placebo in patients undergoing endoscopic endonasal transsphenoidal pituitary surgery. A total of 461 patients were screened for the study...

Endovascular therapies for venous tinnitus

Tinnitus is an extremely vexing issue, not only for patients but also for otolaryngologists. The authors of this article review the causes of venous tinnitus, such as increased intracranial hypertension (IIH), dural venous sinus thrombosis and age-related anatomic variants. They...

Vestibulo-ocular reflex and postural control in deaf children

The authors evaluated the impact of canal paresis detected by video head impulse test (vHIT) on postural control tested by platform posturography in children with sensorineural hearing loss. The study included 55 children (4-16 years old) with variable degrees of...

Septoplasty under local and general anaesthetic

This Turkish prospective, non-randomised study compared the quality of life outcomes in 50 patients who underwent local anaesthetic (LA) septoplasty, and 50 patients who underwent general anaesthetic (GA) septoplasty over a six-month period. Quality of life outcomes were measured using...

How patients reacted to postponement of cochlear implant surgery due to COVID-19

The onset of COVID-19 in 2020 required widespread cancellation of elective surgeries, one of these being cochlear implant for profoundly deafened adults and post-lingually deafened children. Through a questionnaire, to which 23 out of 38 patients responded, this qualitative study...

QoL post-endoscopic hypophysectomy

This prospective study conducted over four years surveyed more than 300 patients after endoscopic pituitary adenoma resection. The authors used the Anterior Skull Base Questionnaire-35 and the Sinonasal Outcome Test-22, and the scores were analysed for quality of life (QoL)...

All you need to know about childhood hearing loss - an update

This is an excellent update on childhood hearing loss. It is a comprehensive collection of five chapters, providing a summary of a broad range of practice guidelines to inform screening, diagnosis, and management of hearing loss in children. It has...

Endoscopic sinus surgery improves Eustachian tube dysfunction

This prospective, multicentre trial from China looked at the improvement in Eustachian tube function after endoscopic sinus surgery. Seventy patients from three tertiary units were included in the study. They all completed the Eustachian tube dysfunction (ETDQ-7) and SNOT-22 questionnaires...

When to operate on a patient without chronic disease?

As ENT surgeons, we spend a lot of time managing chronic rhinosinusitis, so a review and update on the management of the acute disease is always helpful. The standard medical treatment of antibiotics, nasal steroids and nasal decongestants are reported...

Clinical pathological features associated with malignant change in oral leukoplakias

This is a retrospective study from Sweden where 234 patients, diagnosed between 2003 and 2013 with a median nine-year follow-up, were reviewed. Of these 234 patients, 11.5% developed oral squamous cell carcinoma. Non-homogenous leukoplakia showed a 15-times higher transformation rate...