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N-acetylcysteine may have a role in the protection of cochlear hair cells
Gentamycin is an aminoglycoside antibiotic which is widely used throughout the world, despite its ototoxic potential. It therefore seems wise to continue the search for accessible otoprotective agents. The aim of this study was to clarify the potential protective role...
Botulinum toxin in ENT
This comprehensive review neatly summarises non-cosmetic uses of botulinum toxin within otorhinolaryngology, it is perhaps easy to forget the medical use of botulinum toxin has now been approved for the last thirty years. Its overall safety profile places it as...
The Impact of sleep endoscopy for paediatric obstructive sleep-disordered breathing
Paediatric obstructive sleep apnoea (OSA) is not always resolved or improved with adenotonsillectomy. Persistent or complex cases of paediatric OSA may be due to sites of obstruction in the airway other than the tonsils and adenoids. Investigation of paediatric obstructive...
The association of frontal recess anatomy and mucosal disease on the presence of chronic frontal sinusitis: a computed tomographic analysis
Ostial obstruction is a primary pathophysiological mechanism contributing to sinusitis, which can be caused by anatomical variations, mucosal inflammation or both. This retrospective case series aimed to identify anatomical factors and inflammatory areas relating to chronic frontal sinusitis on nasal...
Hearing aid standards and test systems
Hearing aids are the most used management / rehabilitation option for people with hearing loss. Generally, hearing instrument manufacturers perform the hearing aid performance measurements and provide its specification in terms of functionality. However, it is also common for government...
Patients with advanced oral cavity carcinoma are not candidates for the ‘organ preservation’ approach
The authors of this study, from the University of Michigan, evaluated the role of induction chemotherapy for patients with stages III and IV resectable oral squamous cell carcinoma. Nineteen patients were initially enrolled in the induction chemotherapy cohort. Patients with...
Effects of nasal sprays on ciliary function
What do topical nasal sprays do to the nasal mucosa in the long term? This study reports the effect of corticosteroids, antihistamines and common preservatives in nasal sprays, benzalkonium chloride (BKC) and potassium sorbate (PS), on an in-vitro model of...
Thyroid cancer: to dissect the neck or not?
This is a good review of the much-debated management of the neck in thyroid cancer. It discusses oncological goals that must be achieved whilst maintaining voice, swallowing and parathyroid function. A clear description is made of the common nodal basins...
Passive smoking and rhinosinusitis
One would expect that subjects exposed to more passive smoke would have a significantly increased level of rhinosinusitis. This study looked at a reasonable number of sinusitis and control subjects (404 and 165) using hair nicotine as an assessment of...
Friendly bacteria in the ear nose and throat to combat the bad…
The author presents a thorough review of bacterial interference and the studies that have been conducted in common ENT conditions. The simple concept is that a strong population of normal flora will interfere with colonisation and subsequent infection by pathogenic...
Sham controlled trial: BPPV
I was drawn to this study and it proved an enlightening read; it also is a good example of where recommendations of a Cochrane review for long-term evidence of benefit have been acted upon! The study looked at the efficiency...
