You searched for "Genetic"

1309 results found

To scan or not to scan?

This comprehensive review article seeks to establish how useful is MRI in the evaluation of patients with a history of smell loss or distortion. Interestingly, while some studies found the imaging unhelpful, one paper described found a 25% rate of...

Low-frequency air-bone gaps appear to be a true audiological finding in Ménière’s disease

There is a lack of established objective tests in Ménière’s disease (MD) that can provide information about the disease process. The appearance of low-frequency air-bone gaps (LFABGs) in MD is a recognised but unexplored phenomenon. Two theories have been suggested...

Endolymphatic sac tumours

The authors performed a systematic review of literature and describe the clinical signs and symptoms of endolymphatic sac tumours (ELST) in this article. A total of 113 patients and 118 cases from 26 studies were included in the study. The...

Hemilaryngopharyngeal Spasm (HeLPS)

The authors report an unusual case of hemilaryngopharyngeal spasm (HeLPS) with glossopharyngeal neuralgia with otalgia in a middle-aged female patient. Her symptoms included left-sided sharp, electric sensation like pain radiating from her left ear to the left side of her...

Is there a need for magnetic resonance imaging six-month post-radiosurgery for vestibular schwannoma?

With advances in imaging and radiation technologies, small, slowly growing vestibular schwannomas (VS) are treated primarily with either observation or stereotactic radiosurgery (SRS). Routine magnetic resonance (MRI) scans with gadolinium are obtained six months and one year after SRS in...

Endoscopic transsphenoidal surgery versus dopamine agonist therapy for microprolactinomas

This study addresses the importance of the location of microprolactinomas in determining prognosis after surgery. Long-term dopamine agonist treatment is the current standard of treatment for microprolactinomas. However, patients often seek surgical removal. The authors of this study retrospectively analysed...

Algorithm for malignant otitis externa

Timely detection and effective management of this potentially fatal condition cannot be overemphasised. This study presents 16 cases over 12 months in a tertiary referral centre. Most patients had diabetes and others were immunocompromised due to radiotherapy, immunosuppressive medication or...

Reliability of Koos classification

Vestibular schwannoma (VS) tumour size has been considered the primary determinant of hearing outcomes and facial nerve function according to several published studies. Varying methods are used to estimate the size and volume of the VS with very little consensus...

Indication and timing of electrodiagnostic tests in facial palsy

This excellent review describes the benefits and limitations of electrodiagnostic testing for patients with facial paralysis. Tests such as Schirmer, stapedial reflex and electrogustometry have been largely replaced by neurophysiologic tests like nerve excitability test (NET), electroneuronography (ENoG), surface electromyography...

Surgery of vestibular schwannomas with peritumoral oedema

This is an interesting retrospective study evaluating peritumoral oedema on magnetic resonance images and correlating it with the intra-operative tumour characteristics and outcome. The study results found that vestibular schwannomas with peritumoral oedema were associated with greater incidence of hypervascularity...

Role of the insula and orbitofrontal cortex in tinnitus related distress

It is estimated that 5% of the population suffer from chronic tinnitus with 17% of those suffering emotional distress. The authors attempted to study the neural correlates of tinnitus-related distress using functional magnetic resonance imaging (fMRI) during an Emotional Stroop...

Implantable devices and large magnets – do they mix well?

Although all brands are MRI safe at 1.5 T, the active middle ear implant system Vibrant Soundbridge (VSB), is special since it houses two magnets. These include a magnetic floating mass transducer (FMT) and an audioprocessor fixing receiver magnet which...