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Genomic testing for deafness and its implications
Gene therapies for hearing loss are rapidly advancing and will be transitioning to clinical practice. Here, the authors explain why clinicians involved in managing these disorders need to be aware of these advances. Genomic testing in England was significantly reconfigured...The structure and function of DNA
DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...
Temporal Bone Histology and Radiology Atlas
Temporal Bone Histology and Radiology Atlas is an outstanding reference and training manual which will be a rewarding read and purchase for all otolaryngology trainees and, in particular, senior trainees and consultants. Neuro-radiologists and neuro-otologists will enjoy comparing the beautifully-prepared...
Ontogenies of Otology – Vol 1: Anatomy
Whilst there are few who are actively involved in the historical aspects of otology, there always seems to be great interest whenever I introduce the quirks of history into any of my talks. This book, I suspect, will very much...
Laser for active mucosal chronic otitis media
Active mucosal chronic otitis media (COM) is a condition characterised by otorrhoea secondary to chronic inflammation of the middle ear and mastoid mucosa associated with granulations and a tympanic membrane perforation. Surgical intervention is often required, but concurrent mastoidectomy with...
Clinicopathological features of follicular variant of papillary thyroid carcinoma
The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...
Postoperative radiation in early stage oropharyngeal squamous cell cancer (OPSCC)
There is significant variation in treatment strategies for OPSCC between units. This is largely due to unanswered questions which continue to exist beyond the published literature. We know that human papilloma virus status has a significant influence on prognosis but...
