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Gastric inlet patch – an under-diagnosed cause of globus

A gastric inlet patch (GIP) is an island of heterotopic gastric mucosa found commonly in the proximal oesophagus just below the upper oesophageal sphincter. It is often underdiagnosed due to its location. Its importance and clinical relevance can be underestimated...

Patient-led wax and aural foreign body removal technology – is it safe?

As ENT and audiology professionals, wax impaction and aural foreign bodies are common presentations to our clinic that can cause significant distress to patients and can preclude diagnostic testing such as pure tone audiograms and tympanometry. We often advise patients...

Does vestibular rehabilitation help patients with vestibular migraine? Is this also true if these patients have had a traumatic brain injury?

Vestibular migraine (VM) is a common diagnosis in ENT, and there is growing evidence that vestibular rehabilitation therapy (VRT) is an effective treatment, reducing self-perceived dizziness and improving gait. This is a retrospective review of the outcomes of 93 patients...

Investigation of the role of KPNA2 biomarker in oral SCC invasiveness

This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...

ECHNO 2025

The European Congress on Head and Neck Oncology (ECHNO) will be held in Amsterdam in 2025. The strength of the ECHNO meetings is to offer a multidisciplinary podium bringing together professionals from around the world. There will be presentations from...

Neurological idiopathic disease: a shared journey for NASA and medicine

Whilst Southampton can’t really be described as an extreme environment, experiments carried out in the city have certainly been taken out of this world. Robert Marchbanks discusses one of the associations between Southampton, The International Space Station and tympanic membrane...

From Hippocrates to COVID-19: sniffing out the disease

The ancient Greek physician, Hippocrates, used the ‘art of smell’ to diagnose diseases around 400BC. He also formulated miasmatic theory, which posited that disease is caused by bad smells. Bad air was strongly believed by many physicians to be the...

Blood-sampling prognostic predictors for Bell’s palsy

Bell’s palsy is generally defined as an acute-onset unilateral idiopathic mononeuropathy in the facial nerve. It is of unknown aetiology, however, inflammation is considered a major cause. Electroneurography assessing nerve excitability is the most reliable examination for predicting prognosis of...

Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer

The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...

Active surveillance for papillary thyroid cancers – what is the risk of progression?

Papillary thyroid cancers (PTCs) are generally considered to be indolent malignancies with favourable outcomes. Active surveillance (AS) has consequently been trialled as a management option for small PTCs with no evidence of regional lymph node involvement, especially papillary thyroid microcarcinomas...

BPPV duration as a predictor for therapy

Benign paroxysmal positional vertigo (BPPV) is one of the most common vestibuar disorders encountered in the neurotology clinic. The majority of cases of BPPV are due to vestibuar lithiasis in the posterior semicircular canal, but there are reports of cases...

Leightons and The Hearing Care Partnership Opens Registration for Groundbreaking New Clinical Conference: Oxygen 2025

Leightons Opticians & Hearing Care is excited to announce that registration is now open for Oxygen 2025, a pioneering clinical conference taking place on the 9th and 10th of May 2025. This highly anticipated event, hosted by the leading independent,...