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Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours
Introduction Cancer cases continue to increase worldwide, and head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...
Sing it, say it, sort it: singing for Parkinson’s disease
Parkinson’s disease (PD) occurs in 1% of the population aged over 60. Changes in voice and speech are among the earliest and most prevalent symptoms of PD; reduced vocal intensity, monopitch, monoloudness, breathy and hoarse voice quality, imprecise articulation, vocal...
The incidence of coagulopathies in children presenting with post-tonsillectomy haemorrhage
Tonsillectomy is often the first haemostatic challenge for a child. Postoperative haemorrhage may therefore represent the first presentation of a child’s underlying bleeding disorder. This study aimed to quantify the rate of occult coagulopathy in patients who had experienced a...
Cervical tracheal reconstruction
This Chinese animal study looked at the use of a xenogenic acellular dermal matrix for tracheal reconstruction. The authors took a total of 22 rabbits and divided them into an experimental (repair with xenogenic acellular dermal matrix) and control group...
The use of Integra to allow early cover wounds
The authors present the use of Integra in a unique cohort of patients. Seven patients ages 21-31 in a six month period treated in one hospital. These were a very fit group of patients that had injuries caused by improvised...Microneedles enable inner ear precision medicine
Developing safe, reliable and efficient ways to deliver therapeutics into the cochlea is a key challenge. In this article, the authors share their work to develop microneedles to address this challenge. The era of precision medicine of the inner ear...
Management of necrotising otitis externa
Although uncommon, necrotising (previously malignant) otitis externa (nOE) can be very aggressive, particularly if not managed appropriately. In this study the authors perform a retrospective review of 25 patients admitted with nOE over a four year period at a tertiary...The astronomer’s nose: Tycho Brahe’s controversial prosthesis
Tycho Brahe (1546-1601) is a familiar and colourful figure in the history of science. The immense quantity of data he collected during his lifetime would enable the work of Johannes Kepler and has gained him admission to the astronomical pantheon....In conversation with Trevor McGill
After more than four decades of paediatric clinical practice, Trevor McGill shares his wealth of experience and knowledge with Pat Bradley. Trevor, as a national and internationally acknowledged Paediatric Oto-Rhino-Laryngologist, Head and Neck Surgeon, to what do you owe this...
Voice change after total thyroidectomy with intact laryngeal nerves – a common but temporary problem
It has been reported that up to 87% of patients have a degree of voice dysfunction after thyroidectomy, even when the laryngeal nerves are preserved. Postoperative inflammation, laryngeal oedema due to vascular congestion, direct damage to the cricothyroid muscles and...Selecting and optimising hearing aids for tinnitus benefit: a rough guide
Hearing aids have a relatively long history as tinnitus treatment tools. Saltzman and Ersner reported success in suppressing tinnitus with simple hearing aids in a number of cases as early as 1947 [1]. In an early comprehensive approach to tinnitus...
