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CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...
Core or fine needle assessment in lymphadenopathy and salivary gland tumours
This paper from the Republic of Korea analyses 278 patients retrospectively, 112 of which underwent fine need aspiration and 166 core needle biopsies. Eleven patients had indeterminate fine needle aspiration cytology, six of whom had an additional core biopsy. The...
Do you know what aphasia is?
In 2001 a survey was conducted in a number of towns across the world, including Exeter in the UK, to identify the level of awareness and knowledge of aphasia in the community. Aphasia is difficulty in producing or understanding language...
Pedicle calcification – an uncommon problem
This paper from Germany describes an uncommon phenomenon of pedicle calcification in three cases. In patients from two centres that had fibula free flap reconstruction from January 2010 to January 2016, 68 cases had pedicle calcification and three cases were...
Peripheral nerve reconstruction using cell-enhanced acellular nerve grafts
Autologous nerve grafts are the current gold standard for peripheral nerve reconstruction. This systematic review analyses the role of cell-enhanced acellular nerve (ANA) grafts on the regeneration of peripheral nerve injuries. Several studies have been published to examine alternatives to...
Dispelling the myths around stuttering and bilingualism
There are many myths around language development in bilingual children, and an increased risk of stuttering in bilingual children is one of these misperceptions. In research studies, speech and language therapists have identified higher numbers of dysfluencies in speech samples...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
Is there a role for hyperbaric treatment in sudden hearing loss?
Sudden sensorineural hearing loss is a common presentation to ENT departments with a significant difference in management both at a local and regional level. The authors seek to clarify the role of hyperbaric oxygen therapy in combination with oral and...
Laryngeal cleft in a 66-year-old man!
This is a fascinating case report of a 66-year-old man who presented with a carcinoma of the piriform sinus. During chemoradiotherapy, he developed dyspnoea, dysphagia and aspiration pneumonia. His chemoradiotherapy was stopped and he underwent a pharygnolaryngectomy. When the surgical...
Steroids for vocal cord mucus retention cysts
This is an interesting paper that describes the use of intralesional steroid injections to treat vocal cord mucus retention cysts. The gold standard is microlaryngoscopy and excision of the lesion. In patients who may be unable to undergo surgery, this...
Cognition outcomes after cochlear implantation – is there an improvement?
Older adults with a severe to profound hearing loss are more at risk of cognitive decline than adults of a similar age with milder losses or normal hearing. This poses challenges, not only in the assessment process, but also for...
