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Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
COVID-19 tracheostomies
This is a review of tracheostomies completed by an OMFS Unit in London from 10 March to 18 May 2020. A total of 176 COVID-19 patients were admitted to intensive care, 72 of which required tracheostomy due to prolonged respiratory...
Can we avoid FESS in patients with true isolated odontogenic sinusitis?
This is a useful study looking at how best to manage patients with odontogenic sinusitis and if FESS can be safely avoided. The authors treated patients by removing the odontogenic cause of the rhinosinusitis by extracting the offending tooth and...
How to manage the concha bullosa in FESS
It is an interesting concept to assess how much impact the presence of a large concha bullosa (CB) has on both severity of chronic rhinosinusitis (CRS) and also postoperative outcomes after FESS. The authors accept that the paper has limitations...
Paediatric idiopathic sudden sensorineural hearing loss
This Turkish retrospective study looked at the radiological and clinical characteristics, prognostic factors and treatment outcomes in children diagnosed with idiopathic sudden sensorineural hearing loss (ISSNHL). Forty-eight children were included over an eight-year period. Complete recovery (CR) was achieved in...
A safe and useful surgical procedure for allergic rhinitis?
Although the best management of allergic rhinitis is medical, intractable cases are not uncommon. Immunotherapy helps but is more practical if there is a single allergen involved. The authors compare the effects of submucosal inferior turbinoplasty alone with submucosal turbinoplasty...
A cost reducing protocol for magnetic resonance imaging in patients suspected to have acoustic neuroma
Magnetic resonance imaging is the ‘gold standard’ for screening patients suspected to have an acoustic neuroma. However, inappropriate referrals for imaging are not helpful, especially with the growing need to reduce costs. In this study the authors compared two audit...
Closure of septal perforations
This Belgian retrospective observational study looked at the success rate and predictive factors for success when bilateral advancement flaps were used via an external approach. In total, 111 patients were included in the study over a 16-year period. The mean...
Choline PET-CT: an accurate diagnostic tool for the detection of parathyroid adenoma?
Hyperparathyroidism (HPT) is an endocrine disorder characterised by an increase in the secretion of parathyroid hormone (PTH), with a resulting increase in calcium plasma levels, which can cause renal lithiasis, fractures, and osteoporosis, the most frequent symptoms of the disease....
Helicobacter pylori infection delays mucociliary clearance in the nose
Chronic rhinosinusitis is not uncommonly a difficult condition to treat and therefore any possible association of this condition with factors outside the nose and sinuses is the subject of worthwhile research. Impairment of mucociliary clearance is paramount to upper respiratory...
Single surgery for repair of tegmen defects and superior semicircular canal dehiscence
This retrospective review of 34 patients undergoing repair of the temporal bone defect via the middle cranial fossa approach provides the author’s management strategy for two problems: superior semicircular canal dehiscence and tegmen defects. The incidence of both these pathologies...
