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The future of biologics?
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...
Peer-support group for people with a hearing loss
Peer-support groups’ (PSGs) involvement in rehabilitation of people with different health issues can have a very positive impact on the patients’ wellbeing as showed in a various literature on the subject. This study involves analysis of data from previous studies...
A new criterion for diagnosing chronic tonsillitis?
It is essential to establish the diagnosis of recurrent tonsillitis in patients undergoing tonsillectomy. This is based mainly on history which itself can be inaccurate and is supported by clinical findings which are not truly specific. There seems to be...
Office-based intralesional corticosteroids injections for subglottic stenosis. Is it effective?
Subglottic and proximal tracheal stenosis in adults has three main aetiologies: (a) prolonged endotracheal intubation; (b) idiopathic; (C) rheumatologic related. Endoscopic dilation is the mainstay treatment strategy for subglottic and proximal tracheal stenosis. Its major limitation is restenosis requiring repeated...
QOL studies for anterior skull base surgeries
The Anterior Skull Base Nasal Inventory-12 (ASK Nasal-12) is a standard tool for assessment of quality of life (QOL) in patients who have undergone endonasal transsphenoidal surgery. As nasal trauma and rhinological complications following endonasal transsphenoidal surgery can influence QOL,...
Motor learning: better knowing how, not how well
Motor learning is described as the ability to perform a motor skill due to practice and/or experience. Research on interventions to enhance limb motor skills can be influenced through the amount, distribution, variability and schedule of practice as well as...
IL-25 and nasal polyps, another target
Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...
Tinnitus and Sound Sensitivity Case Book
This book, as the title suggests, is full of case studies written by health wprofessionals involving patients who are experiencing tinnitus and/or sound sensitivity. There are 29 different case studies spanning both adults and paediatrics (though mainly adults). Each case...
Speech Sound Disorders: Comprehensive Evaluation and Treatment
As an audiologist specialising in paediatrics, I reviewed this book out of interest to hopefully broaden my knowledge of a somewhat related subject. I found this an interesting read with some good points made, such as the long-term outcomes for...
Handbook of Otolaryngic Allergy
This book is an excellent companion for doctors dealing with allergy and rhinological complications of allergy. It contains detailed information of immunological pathways, from cells to systemic effects, of cellular reaction. It is well organised and takes the reader through...
Sublingual house dust mite immunotherapy
House dust mite immunotherapy in allergic rhinitis was shown to be effective in trials with a relatively small number of participants. The authors of this study performed a multicentre double-blind randomised controlled trial to investigate effects of house dust mite...
