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Vascularised tissue in salvage total laryngectomy
Chemoradiation (CRT) has become the mainstay for locally advanced laryngeal cancer since the RTOG 91-11 trial. Unfortunately there is still a substantial demand for salvage laryngectomies, which have a higher complication rate, the most notable being pharyngocutaneous fistula (PCF). Several...
Treatment options for vestibular neuritis: systematic review and meta-analysis
Vestibular neuritis (VN) is the third most common cause of peripheral vertigo. VN has been postulated to have viral aetiology and historically it was treated with steroids, until 2011 when a Cochrane review demonstrated lack of robust evidence behind this...
Training people with Parkinson’s disease and their partners to have better conversations
Parkinson’s disease is predominantly considered a motor disorder, impacting speech, particularly voice volume, amongst other physical functions. Language and cognitive difficulties, such as difficulties in word finding and social pragmatics are also a key feature of Parkinson’s disease. Given the...
Balloon Eustachian tuboplasty – is it time to start doing it in children?
Given the potential applications for balloon Eustachian tuboplasty (BET) in children, its uptake in most centres has been slow. The reasons for this are multifactorial. There are technical issues – the feasibility of obtaining the correct size balloon and manoeuvring...
Immunosuppresants and ototoxicity
There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...
Is there an association with cognitive impairment and hearing loss in a developing country?
Hearing loss (HL) is the third leading chronic health condition among older adults. Most studies investigating HL and cognition have been performed in high-income countries. Risk factors for dementia (eg. hypertension, midlife hearing loss, obesity and physical inactivity) are more...Trainee-led collaborative research and audit in ENT: where are we now?
In late 2015 INTEGRATE, the UK ENT Trainee Research Network, was formed. Since then, two national projects have been completed and INTEGRATE has grown into a larger, more structured organisation, with otology, head and neck and rhinology subcommittees working alongside...
Does balloon tuboplasty work in the long term, and how can we measure outcomes?
There is much interest and debate at ENT conferences and within current literature about the role of balloon dilatation techniques for Eustachian tube dysfunction (ETD), a condition which we still only have limited understanding of, and which can be challenging...
Sarcopenia and dysphagia in older community-dwelling adults
The prevalence of dysphagia in community-dwelling older adults is reported to be around 15%. Outside of common neurological causes such as stroke, Parkinson’s disease and dementia, recent studies have suggested that sarcopenia may be an independent risk factor for the...
An alternative device for obstructive sleep apnoea
Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep apnoea (OSA), primarily due to the vast amount of short-term evidence in the medical literature it has accrued. The enduring obstacle to CPAP from becoming a treatment option...
Intratympanic steroids - to give or not to give?
The treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) is controversial and different modes of steroids have been tried without any universal consensus. Various authors have reported combined oral and intratympanic steroid therapy in SSNHL, with consistent results in several...
