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Pre-clinical development of magnetic delivery of therapy to middle and inner ears

Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...

Practical Neurotology and Skull Base Surgery

The introduction describes this text as being useful for a wide readership including the medical student, physician assistant, nurse practitioner and physical therapist dealing with dizziness. I would be of the opinion as indicated in the preface that this is...

Impedance for different electrode types

Measuring cochlear implant (CI) electrode impedances is common in CI programming appointments to measure the integrity of the implant e.g. whether there are any open or short electrodes. This is because impedance measures the flow of current between intra and...

A surgeon’s perspective on the challenges facing cochlear implantation in children

Cochlear implantation in children offers a different set of challenges and goals to adult practice. In this article, Iain Bruce, Professor of Paediatric Otolaryngology in Manchester, UK, explains some of the current clinical and research challenges in paediatric cochlear implantation,...

Recording of electrode voltages (REVS) to determine extra-cochlear electrodes

Determining whether electrodes are sitting within the cochlea can be difficult as the checks run by the programming software cannot always determine this. In some cases, patients may be unable to give the audiologist detailed feedback which can complicate the...

Early cochlear implant activation and its effects on the cochlea

In this article, Alhabib et al consider the changes to electrode impedance with early device activation (day one) compared to conventional activation (day 30). Activation at day 30 is a cautious approach, which has been popular for many years. However,...

The polyp shrinker

Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...

Does stress and anxiety worsen idiopathic sudden hearing loss outcomes?

There have been suggestions that the natural course of the idiopathic sudden sensorineural hearing loss (ISSNHL) is not affected by intensive therapy. There is speculation as to whether unknown factors affect the treatment prognosis. This is a retrospective study of...

Ontogenies of Otology – Vol 1: Anatomy

Whilst there are few who are actively involved in the historical aspects of otology, there always seems to be great interest whenever I introduce the quirks of history into any of my talks. This book, I suspect, will very much...

SPECT-CT imaging improves surgical efficiency in sentinel lymph node biopsy in melanoma

Sentinel lymph node biopsy is used in clinically lymph node negative, primary cutaneous melanoma. A combination of planer lymposcintigraphy using a radiolabelled colloid detected intra-op by gamma probe, and cutaneous injection of blue dye is used. However, with lymphoscintigraphy spillage...

Parathyroid pearls

This article serves to deliver some pearls of wisdom in parathyroid surgery for the ‘low volume parathyroid surgeon’. They have been divided into those relating to the preoperative diagnosis, imaging and localisation techniques and surgical difficulties. Recognised sources of error...

Cochlear implant electrode insertion technique

Atraumatic cochlear implant insertion techniques (so-called ‘soft surgery’) are now standard practice in most centres for all cases (no longer just for attempted hearing preservation cases). This has led to several studies examining cochlear trauma and electrode insertion force. In...