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3019 results found

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Developmental language disorder

Disorders such as attention deficit disorder (ADHD), autism spectrum disorder and developmental dyslexia have received widespread recognition. As a result, children affected by these conditions are able to receive remedial services. In this article, the author discusses the possible reasons...

Do nasal septal deviation and septoplasy affect Eustachian tube function?

The authors suggest that nasal septal deviation (NSD) or septoplasty possibly affect Eustachian tube (ET) function. They conclude this from their prospective study on 25 patients who underwent septoplasty for NSD. These patients aged above 14 years had no other...

Diagnosis of obstructive sleep apnoea hypopneoa syndrome (OSAHS) without sleep studies

Polysomnography is considered the ‘gold standard’ in the diagnosis of sleep apnoea but it is expensive and difficult to perform in children. Diagnosis based on subjective judgement is often inaccurate. An accurate diagnostic scale based on clinical parameters could obviate...

Are cardiovascular risk factors associated with hearing loss?

Cardiovascular disease (CVD) risk factors are associated with microvascular damage that can impair molecular transport across capillary walls and cause inflammation and oxidative stress that may damage cochlear structure and function. This study determined, among a population-based sample of Canadian...

Should we reconsider induction chemotherapy in advanced stage laryngeal cancer?

Use of chemo-radiotherapy for advanced laryngeal cancer led to a major shift in treatment as an alternative to total laryngectomy. Despite widespread adoption of chemoradiotherapy, survival rates have not improved and the original premise of matching neoadjuvant chemotherapy tumour response...

‘What was I talking about?’ Memory and discourse in language impairment

This article discusses the function of the three theoretical components of working memory and their influence on discourse (the phonological assembly, the visuo-spatial sketchpad and the episodic buffer). The authors emphasise that the buffer is the key conceptual component responsible...

Literature review of experience with the BAHA Attract implant

The authors undertook a literature review for reports on patients who underwent BAHA Attract implantation. Of the 497 PubMed articles, 10 studies met their inclusion criteria. All the studies published were observational studies. There were no randomised control trials. The...

Transoral surgery for submandibular stones

The authors assessed the factors that influence the outcome of transoral excision of submandibular duct stones. This was a retrospective case-note review and prospective telephone survey of 125 patients, who had surgery over an eight-year period by a single surgeon....

Sharing audio data for the greater good of research

HomeBank is a novel online repository for daylong audio recordings of children and families. Daylong recordings of children in naturalistic environments with their family and friends are an important source of information to enable an understanding of how children develop...

Classification and assessment of midfacial fractures; no more Le Fort facial fractures

There is some evidence that severe or complex midfacial or orbital fractures have declined over the last decade. Interestingly there is also evidence of an increase in road traffic accidents but a decrease in facial injuries. This is possibly attributed...