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Precision and personalised genomic and epigenomic medicine in audiology/hearing loss
A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...Assessment of genetic disorders: congenital sensorineural hearing loss
Severe or profound sensorineural hearing impairment (SNHI) is a common birth defect, affecting approximately 1 in 1000 newborns [1]. SNHI may result from environmental causes or have a genetic basis. The genetic causes can be further subdivided into non-syndromic (isolated...In conversation with Professor Jos Eggermont
Having known Jos for many years, I jumped at the opportunity to catch up with him for our Nov/Dec 2020 series of tinnitus items. My questions reached him during lockdown, and he was enjoying the chance to get on top...Adjoin™ bone conduction system
Patrik Westerkull (PW), Otorix AB, and Ann-Louise McDermott (A-LM), ENT Consultant at Birmingham Children’s Hospital, tell us about the Adjoin bone conduction device, a non-surgical bone-conduction option developed by Otorix. They explain how the product works, the background to the...Illuminating ear education: building interactive models to enhance inner ear understanding
Understanding the anatomy and function of the inner ear, particularly the vestibular apparatus and cochlea, is fundamental to audiology and otolaryngology education. However, the complex geometry and intricate functional relationships of these structures challenge us to find clear ways to...
DISE as a rationalising tool for sleep apnoea surgery
This retrospective study on 85 adult obstructive sleep apnoea (OSA) patients provides further interesting information for sleep surgeons. These patients were all investigated with polysomnography (PSG) and drug induced sleep endoscopy (DISE). They all then underwent a simple uvulopalatoplasty with...
The sleep nasendoscopy learning curve
There seems to be no accepted way of surgically assessing patients with sleep disordered breathing (SDB). Because of this, clinicians fall roughly into three camps: those who just use one operation for all patients, those who have given up surgery...Developing medical devices for children: opportunities and challenges
The development of medical devices for infants and children lags significantly behind the development of devices for adults. While in the United States the Food and Drug Administration (FDA) has set up incentives for developing child age-specific pharmaceuticals, there is...Communicating with patients in ‘Plain English’
Physicians have long been accused of using unnecessarily complicated language and impenetrable jargon as a way of maintaining their status, prestige and high earnings-potential, bamboozling the public and excluding them from meaningful discussion as part of what George Bernard Shaw...Public Health Planning for Hearing Impairment (2022)
The World Report on Hearing, published in 2021 by the WHO reports that 430 million people in the world have moderate or worse hearing loss, all of whom require rehabilitation [1]. Over 1.5 billion have any degree of hearing loss....A new clinical device to monitor nasal blockage
Chia-Hung Li, a Medical Device PhD student from University College London’s (UCL) Institute of Healthcare Engineering, is currently leading a PhD project to develop a clinical device to monitor nasal blockage. Jo Rimmer spoke to him about what he is...
