You searched for "trial"
Matthew Clark: full-time otologist, spare-time sculptor
1 July 2018
| Matthew Clark
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ENTA - ENT
Drilling a temporal bone may seem like torture to some trainee surgeons. To others it is but a stepping stone to something altogether grander... I took Art A-level a year early so as not to interfere with the ‘important subjects’,...
Implant patient says it with flour
30 May 2024
So delighted was 77-year-old Graham with his cochlear implant, he asked his granddaughter Lillie Westbury, a professional baker, to bake an “ear” cake.
Young ESPO - calling all young paediatric otolaryngologists
5 October 2020
Young ESPO welcomes all junior otolaryngologists with a special interest in paediatrics to become part of a community of training doctors, and share clinical and research knowledge on paediatric ENT!
Hypoglossal nerve stimulation for OSA
1 November 2019
| Vik Veer
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Otology
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Hypoglossal nerve, Long term, Obstructive sleep apnea, Stimulation, Upper airway
Hypoglossal nerve stimulation has been lauded as the great new surgical treatment panacea for obstructive sleep apnoea (OSA). This meta-analysis includes 12 studies with a total of 350 patients, including the five-year follow-up data from the STAR trial which was...
Medical trends in sleep disordered breathing
1 January 2016
| Suzanne Jervis
This duo provide an eloquent outline of sleep disordered breathing in general, with particular emphasis on the medical impact and associations of the condition. The increasing prevalence of the condition is described, with increasing worldwide obesity, increased association of cardiac...
Genetic discovery using animal models: presbyacusis
By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...One airway, one disease - not for everyone!
3 March 2021
| Hassan Mohammed
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ENTA - Rhinology / Sinus
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asthma, atopic dermatitis, multimorbidity, rhinitis, transcriptomics
While 85% of asthmatic patients have rhinitis, only 20-30% with rhinitis have asthma. Together with atopic dermatitis (AD), rhinitis and asthma form a triad that tend to co-exist in patients (multimorbidity). This co-existence raises the possibility of genetic mechanism. Authors...
A new hydrogel dural sealant for CSF repair
1 July 2017
| Gauri Mankekar
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Spontaneous cerebrospinal fluid leaks, Dural repair, Dural sealant, Hydrogel, dermatology
This paper reports the findings of a multicentre prospective randomised trial conducted to demonstrate the efficacy of the Adherus Dural Sealant for FDA approval. The Adherus Dural Sealant was compared with the control, DuraSeal Dural Sealant. It was applied to...
Medical control of allergic rhinitis in children
1 July 2017
| Hassan Mohammed
The authors of this randomised trial aim to answer an important question – which is better: daily versus on demand use of intranasal steroids (fluticasone probionate) or antihistamines (levocetirizine dihydrochloride) for symptomatic control of allergic rhinoconjunctivitis secondary to pollen? The...
SpeechEasy® for stuttering
In this article, the authors describe their experiences with an altered auditory feedback (AAF) device: SpeechEasy® during a random clinical trial. AAF has been reported in other laboratory studies to reduce stuttering events without influencing the rate, intensity or frequency...Hypoglossal stimulation for OSA
1 May 2016
| Thomas Jacques
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apnea hypopnea index, clinical, cranial nerve, device, hypoglossal nerve, implant, long term, obstructive sleep apnea, quality of life, sleep
Continuous positive airway pressure (CPAP) is a highly effective treatment for moderate-to-severe obstructive sleep apnoea (OSA), but suffers significantly from poor patient adherence. This paper reports the three-year outcomes of a prospective multicentre cohort study examining the effect of hypoglossal...
Clonidine based vs Remifentanil based hypotensive anaesthesia in FESS
1 September 2015
| Suki Ahluwalia
A study investigating the use of clonidine preoperatively in FESS surgery. A double blinded trial of 47 patients in Barcelona randomised into receiving clonidine (20 minutes preoperatively) versus Remifentanil (continuous infusion). Propofol and fentanyl were used for induction and then...