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Gastro-oesophageal reflux and cricopharyngeal dysfunction – how do they link?
It has been hypothesised that cricopharyngeal muscle hypertrophy develops as a response to chronic gastro-oesophageal reflux disease. The cricopharyngeus muscle is an important component and contributor to the upper oesophageal sphincter that creates a barrier between the pharynx and oesophagus....
Are upper respiratory symptoms and macroscopic changes in children always due to gastro-oesphageal reflux?
In children, symptoms such as chronic cough, wheezing, stridor, voice changes, persistent asthma and dental erosion are often presumed to be due to gastro-oesophageal reflux and empirical treatment with PPIs is offered. Usual investigations, such as a barium meal, gastroscopy...
Electrodes and the stapedial reflex
This study had two main objectives: testing the efficiency of the sequential stimulation of four different electrodes versus a single electrode on the threshold of the stapedial reflex; and correlating the values with the minimum comfort level (MCL). The study...
Salivary pepsin – a simple test for LPR?
A diagnosis of laryngopharyngeal reflux (LPR) can be made on the basis of characteristic symptoms and nasendoscopy findings. Objective tests exist for this condition; for example, 24-hour dual-channel pH-metry which is considered to be the gold standard. Such tests are,...Peptest Q&A
Untreated reflux can cause inflammation, scarring, narrowing and precancerous changes in the oesophagus and larynx, and may increase the risk of asthma and sleep apnoea.Minimise waiting times with Peptest!
In laryngopharyngeal reflux (LPR), refluxed stomach contents travel up the oesophagus and reach the larynx, causing chronic extra-gastrointestinal symptoms such as a persistent cough, hoarseness or difficulty swallowing, meaning it is often attributed to ENT problems.Streamlining ENT pathways
Laryngopharyngeal reflux (LPR) may present with severe extra-gastrointestinal symptoms – including a persistent cough, vocal problems, asthma or difficulty swallowing – that can be incorrectly attributed to ENT problems because patients and GPs alike assume they stem from colds, allergies or over-using the voice.Reza Band<sup>®</sup> UES Assist Device
Members of the ENT and Audiology News team spoke to Rose Henrichs, Solutiones Vobis and Nick Maris, CEO and President of Somna Therapeutics about the Reza Band device. Nick Maris. Rose Henrichs. What is your involvement in Reza Band? And...Pepsin detection in the diagnosis of LPR: New webinar available on-demand
BIOHIT HealthCare has staged an on-demand webinar about the clinical application of pepsin measurement in the investigation of reflux.
A histological test for LPR?
Laryngopharyngeal reflux (LPR) is often considered to be a contributory factor to the development of a spectrum of laryngeal abnormalities including vocal cord leukoplakia and dysplasia. This is especially the case when traditional risk factors, such as tobacco smoking, are...
Bile acids and pharyngeal malignancy
Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...
