You searched for "papillomatosis"

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Laryngeal disorders associated with HIV infection

Following the introduction, and now widespread availability, of combined antiretroviral therapy, HIV has become a chronic disease with minimal or indeed no negative impact on life expectancy. As a result, there is a growing public health interest in establishing the...

Gardasil vaccination – an effective adjuvant therapy for RRP?

The clinical manifestations of recurrent respiratory papillomatosis (RRP) can vary hugely from individual to individual. Whilst some affected children will outgrow the disease, a subset of patients will experience frequent recurrences and require multiple surgical procedures over the course of...

An update on HPV and the vaccination

In recent years, the role of HPV in the development of oropharyngeal cancers has become apparent. Hannah Fox and Vin Paleri contend that while we may not always be able to cure oropharyngeal cancers, vaccination offers our best hope for...

Recurrent respiratory papilloma treatment in the office

In this interesting new article, Markus Hess and Susanne Fleischer describe their technique for managing recurrent laryngeal papillomatosis in an outpatient setting using channelled endoscopes. The recurrent respiratory papillomatosis (RRP) of the larynx is a chronic HPV-associated viral disease. Clinical...

Manual of Allergy and Clinical Immunology for Otolaryngologists

As a first approach, the book impresses with the hardback cover and the glossy 442 pages. Published in March 2015, the book reflects an effort to deliver the main advances and updates of allergy and clinical immunology relevant to otolaryngology...

The stigma of HPV in oral cancer

The increase of oropharyngeal carcinoma (OPC) in the developed world seems to be largely caused by infection with the human papillomavirus (HPV). HPV is a group of 150 DNA viruses that are common and most people will be infected at...

What’s new in laryngology: the next 10 years!

At a time of unprecedented technological advances, Taran Tatla and Jonathan Fishman gaze into the laryngological crystal ball… Introduction The recent explosion in science, technology and innovation takes us into a new era, with the opportunity and capability to transform...

1st World Congress of Paediatric ENT — In the 21st Century

Report by: Professor Ray Clarke, Alder Hey Children’s Hospital, Liverpool, UK Some 2000 delegates from 60 countries gathered in Buenos Aires in April to share their experiences and expertise in paediatric otolaryngology. Congress President, Professor Tania Sih, has long had...

Difficult consultations with HPV-positive oropharnyeal cancer patients

The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...

Multisystem pathology in refractory otitis media with effusion

Recurrent middle ear effusion is a common problem and so is rhinosinusitis with polyposis. It is not often thought that the problem could be linked to multisystem pathology, such as eosinophilic granulomatous with polyposis. Therefore, repeated grommet insertions and surgical...

Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer

The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...

Impact of the updated cancer staging system on HPV-positive disease

The AJCC cancer staging manual was updated in 2017 (8th edition). It is used in the MDT setting for planning treatment and assessing prognosis for individual patients, and is also widely used internationally in clinical trials. Unlike previous iterations of...